HE Sheng, ZHOU Xing-zi, HE Hai, et al. Research Progress of Alkaloids in Mori Folium[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(13): 222-226.
DOI:
HE Sheng, ZHOU Xing-zi, HE Hai, et al. Research Progress of Alkaloids in Mori Folium[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(13): 222-226. DOI: 10.13422/j.cnki.syfjx.2015130222.
Mori Folium is one of traditional Chinese medicines in China. Eight monomer alkaloids have been isolated from Mori Folium. Modern pharmacological studies have confirmed that these compounds have efficient activities of glucosidase inhibition
insulin secretion and inhibition of glycogenolysis. This article focused on the research progress of the monolithic structure
biological activity
extraction and purification technology and testing methods
by studying the chemical structure and properties of alkaloids
and analyzing its various content detection methods
to provide reference for the improvement of detection method of alkaloids. The current method for the determination of Mori Folium alkaloids focused on the study of its deoxynojirimycin(DNJ)
relatively few studies on the total alkaloids content. On the basis of DNJ determination method
it is necessary to establish an appropriate method for the determination of total alkaloids Mori Folium
thus to provide a basis for the rational development and utilization of Mori Folium resources.
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