Objective: To investigate the inhibition of pancreatic lipase and antioxidation of different extracts from Platycladus orientalis leaves in vitro. Method: The inhibitory activities of pancreatic lipase of ethanol extract

petroleum aether extract

ethyl acetate extract

n-butyl alcohol extract and water extract were assayed in vitro. The antioxidant activities of these extracts were assessed by two complementary test systems

namely 1

1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and ferric reducing antioxidant power(FRAP) assay. Result: The ethyl acetate extract showed strong activity in the inhibitory activities of pancreatic lipase (IC50 26.09 mg · L-1). The n-butanol extract (IC50 39.02 mg · L-1) and ethanol extract (IC50 98.20 mg · L-1) displayed lower activity. Petroleum ether extract (C50 188.27 mg · L-1) and water fraction (IC50 325.28 mg · L-1) have a little activity. The antioxidant activities:ethanol extract (DPPH IC50 7.59 mg · L-1

FRAP 4.40 mmol ·g-1) >ethyl acetate extract (DPPH IC50 8.28 mg · L-1

FRAP 3.82 mmol · g-1)>n-butanol extract (DPPH IC50 24.21 mg · L-1

FRAP 1.77 mmol · g-1)>water extract (DPPH IC50 27.53 mg · L-1

FRAP 1.38 mmol · g-1)>petroleum ether extract. Conclusion: The ethyl acetate extract and n-butanol extract were the components of inhibition pancreatic lipase. The ethyl acetate extract was the antioxidative components.