WU Li-hong, CHEN Qiao, ZHANG Bo. Clinical Observation of Niaoduqing Particles Gouty Nephropathy with 49 Cases[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(14): 157-160.
DOI:
WU Li-hong, CHEN Qiao, ZHANG Bo. Clinical Observation of Niaoduqing Particles Gouty Nephropathy with 49 Cases[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(14): 157-160. DOI: 10.13422/j.cnki.syfjx.2015140157.
Clinical Observation of Niaoduqing Particles Gouty Nephropathy with 49 Cases
Objective: Discuss protection effect of Niaoduqing particles combined conventional western medicine therapy treat gouty nephropathy renal function. Method: Ninety-nine patients were randomly divided into control group(49 cases) and observation group(50 cases). Patients in control group took allopurinol tablets on the basis of adjusting the diet habit
100 mg/time
2 does/day. Sodium bicarbonate tablets
1 g/time
3 does/day. Based on the therapy in control group
patients in observation group added Niaoduqing particles
5 g/time
3 does/day
taken with boiled water. Treatment courses in two groups were both 12 weeks. Observe indicators changes as 24 h urine protein quantitative (Upro)
urine routine
creatinine (Cr)
blood urea nitrogen (BUN)
uric acid (UA)
urinary inhibition-C(Cys-C)
β2-microglobulin (β2-MG)
urinary n-acetyl-β-amino glycosidase enzymes (NAG) and xanthine oxidase (XOD) before and after treatment. Score the lienal kidney deficient empty and wet muddy resistance card symptoms before and after therapy. Result: By Ridit analysis
the disease curative effect and traditional Chinese medicine syndrome curative effect in observation group were superior to those in control group(P<0.05). Levels of Upro
Cr
BUN and UA in observation group were inferior to the standards in control group(P<0.05
P<0.01). XOD
Cys-C
β2-MG and NAG in observation group were less than those in control group(P<0.05
P<0.01). Conclusion: Based on lifestyle intervention and conventional western medicine treatment
Niaoduqing particles can reduce Upro
Cr
BUN
UA
XOD
Cys-C
β2-MG and NAG levels with gouty nephropathy disease. It has certain protective effect for renal function. Its disease curative effect and traditional Chinese medicine syndrome curative effect are superior to using western medicine therapy alone.
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