Objective: The purpose of this study was to investigate the clinical effect of treatment of Tongqiao Biyan particles in combination with acupuncture in allergic rhinitis (AR)

and its effects on levels of serum interleukin(IL) -4

IL-6

IL-10. Method: One hundred and ten cases of AR meeting the inclusion criteria were randomly divided into two groups equally. Besides conventional treatments

the control group was treated with Tongqiao Biyan particles

while the observation group was treated with Tongqiao Biyan particles and acupuncture. Then

the curative efficacy

clinical symptoms scores and inflammatory factors of IL-4

IL-6

IL-10 and recurrence rate were observed and compared. Result: The observation group had a total therapeutic efficiency of 96.4%

which was significantly higher than that 85.4% in the control group (P<0.05). In comparison with the control group

scores of sneeze

nasal mucus

nasal congestion and nasal itching in the observation were all statistically lower (all P<0.05). As to inflammatory factors

levels of IL-4

IL-6 and IL-10 in the observation group were statistically lower than those in the control group (all P<0.05). After the six-month follow-up

the recurrence rate in the observation group was 5.4%

which was statistically lower than 18.2% in the control group (P<0.05). Conclusion: Combined treatment of Tongqiao Biyan particles with acupuncture for AR is effective

which can significantly increase curative efficacy

improve clinical symptoms and alleviate inflammatory reaction with low recurrence rate.