PAN Ming-ming, CAI Jian-xiong, WANG Yi-ting, et al. Meta-analysis of Randomized Controlled Trials Yanhuning Injection for Treatment of Hand-foot-mouth Disease[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(14): 209-215.
DOI:
PAN Ming-ming, CAI Jian-xiong, WANG Yi-ting, et al. Meta-analysis of Randomized Controlled Trials Yanhuning Injection for Treatment of Hand-foot-mouth Disease[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(14): 209-215. DOI: 10.13422/j.cnki.syfjx.2015140209.
Meta-analysis of Randomized Controlled Trials Yanhuning Injection for Treatment of Hand-foot-mouth Disease
Objective: To system atically review the effective ness and safety of Yanhuning for curing the hand-foot-mouth disease (HFMD). Method: Methods included a structured search strategy on The Cochrane Library
EBSCO
EMbase
PubMed
CBM
VIP
CNKI and Wanfang Data data bases;randomized controlled trial (RCT) of HFMD relevant Yanhuning treatment of search
were searched from inception to 2014 October;according to the inclusion and exclusion criteria in dependent screening literature
data extraction and quality assessment
Meta-analysis was carried out using Rev Man 5.3 software. Result: 51 RCT were included
7 718 cases. Results showed that:Yanhuning or Yanhuning combined Ribavirin group's efficiency in patients with fever
total time
ulcers resolve time have more advantages than single Ribavirin
with statistical difference. In the aspec to fsafety
Yanhuning injection group
the incidence rate of adversea ction was 2.48%
slightly lower than the Ribavirin group 2.57%. Conclusion: Yanhuning injection in the treatment of HFMD has good curative effect and low incidence rate of adverse action.But because of the overall poor quality into literature
RCT is needed to design multi center
large sample of more rigorous further confirmed the conclusion.
Systematic Review on Yanhuning Combined with Ribavirin in Treatment of Hand-food-mouth Disease
Meta-analysis of Xiyanping Combined with Ribavirin in Treatment of Children with Hand-foot-mouth Disease
Xiyanping Combined with Ribavirin in Treatment of Children with Pediatric Herpangina
Meta-analysis of Yanhuning Injection Combined with Interferon for Treatment of Hand-foot-mouth Disease
Meta-analysis and Grade Evidence Evaluation of Qi-reinforcing and Blood-activating/ Stasis-expelling Chinese Patent Medicines in Treatment of Coronary Microvascular Disease
Related Author
LUO Qin-hong
GU Zi-juan
LIANG Jin-zhi
FANG Yi-sheng
XU Jing-li
HUANG Chao-yuan
LIANG Zheng-rong
DENG Lu-ming
Related Institution
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed by Henan Province and Education Ministry of P.R. China/Henan Key Laboratory of Chinese Medicine for Respiratory Disease,Henan University of Chinese Medicine
The First Affiliated Hospital of Henan University of Chinese Medicine
The First Clinical Medical School of Henan University of Chinese Medicine
The First Clinical College of Nanjing University of Chinese Medicine