DU Juan. Effect of Bushen Tiaojing Decoction in Promoting Ovulation Among Polycystic Ovarian Syndrome Barrenness Patients[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(16): 171-174.
DOI:
DU Juan. Effect of Bushen Tiaojing Decoction in Promoting Ovulation Among Polycystic Ovarian Syndrome Barrenness Patients[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(16): 171-174. DOI: 10.13422/j.cnki.syfjx.2015160171.
Effect of Bushen Tiaojing Decoction in Promoting Ovulation Among Polycystic Ovarian Syndrome Barrenness Patients
Objective: To discuss the efficacy of Bushen Tiaojing decoction in promoting ovulation among patients with polycystic ovarian syndrome (PCOS) and its effect on insulin resistance (IR) and serum leptin (LP). Method: Totally 114 patients were divided into the control group (57 cases) and the observation group (57 cases) by the random number table. Patients in the control group received ethinylestradiol and cyproterone acetate tablets and clomiphene citrate. Besides the therapy of the control group therapy
patients in the observation group were also given Bushen Tiaojing decoction. The treatment courses for both groups lasted for 3 menstrual cycles. The endometrial thickness
endometrium types (A
B
C)
cervical mucus scores
number of eggs ovulated
menstruation recovery
encyesis were observed. The insulin resistance index (HOMA-IR)
leptin (LP)
luteinizing hormone (LH)
serum testosterone (T)
estradiol (E2) and follicle stimulating hormone (FSH) were detected. Result: After the treatment
the endometrial thickness and cervical mucus scores in the observation group were higher than that in the control group (P <0.01). After the treatment
type A endometrium in the observation group was higher than that in the control group (P <0.05). The menstruation recovery
number of eggs ovulated
encyesis in the observation group were higher than that in the control group (P <0.05). T
LH
HOMA-IR and LP levels in the observation group were lower than that in the control group (P <0.01). Conclusion: Combined with the western therapies
Bushen Tiaojing decoction can improve endometrial thickness and endometrial morphology
promote menstruation recovery
induce ovulation and enhance encyesis. Its mechanism may be correlated with the regulation of endocrine and metabolism.