Clinical Observation of Comprehensive Traditional Chinese Medicine Therapy in Treating 60 Cases with Hepatocirrhosis Ascites (Spleen and Kidney Yang Deficiency and Water Retention Symptoms)
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Clinical Observation of Comprehensive Traditional Chinese Medicine Therapy in Treating 60 Cases with Hepatocirrhosis Ascites (Spleen and Kidney Yang Deficiency and Water Retention Symptoms)
Chinese Journal of Experimental Traditional Medical FormulaeVol. 21, Issue 16, Pages: 179-182(2015)
LI Yan-ling, ZHAI Yu-feng, ZHANG Huai-hong, et al. Clinical Observation of Comprehensive Traditional Chinese Medicine Therapy in Treating 60 Cases with Hepatocirrhosis Ascites (Spleen and Kidney Yang Deficiency and Water Retention Symptoms)[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(16): 179-182.
DOI:
LI Yan-ling, ZHAI Yu-feng, ZHANG Huai-hong, et al. Clinical Observation of Comprehensive Traditional Chinese Medicine Therapy in Treating 60 Cases with Hepatocirrhosis Ascites (Spleen and Kidney Yang Deficiency and Water Retention Symptoms)[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(16): 179-182. DOI: 10.13422/j.cnki.syfjx.2015160179.
Clinical Observation of Comprehensive Traditional Chinese Medicine Therapy in Treating 60 Cases with Hepatocirrhosis Ascites (Spleen and Kidney Yang Deficiency and Water Retention Symptoms)
P <0.01);治疗后ALB水平组间比较差异无统计学意义;治疗后观察组脾肾阳虚证和Child-Pugh评分均低于对照组(P <0.01)
体重轻于对照组(P <0.05)
腰围小于对照组(P <0.05)
24 h尿量多于对照组(P <0.01)。 结论: 在西医常规治疗的基础上
中医综合疗法能改善肝硬化腹水(脾肾阳虚水停证)患者的肝功能
减轻临床症状、体征
促进腹水的消退
其综合疗效和中医证候疗效均优于单纯西医治疗。
Abstract
Objective: To observe the clinical effect of the comprehensive therapy of intake of Jiawei Fuzi Lizhong decoction
application on Shenque acupoint and moxibustion in treating hepatocirrhosis ascites (spleen and kidney yang deficiency and water retention symptoms). Method: Totally 118 patients were randomly divided into the control group (58 cases) and the observation group (60 cases). The control group stayed in bed
took less sodium and limited liquid infusion to balance water
electrolyte and acid-base value
and received therapies for liver protection and diuresis. Based on the therapies of the control group
the observation group additionally received the comprehensive traditional Chinese medicine therapy of intake of Jiawei Fuzi Lizhong decoction
application on Shenque acupoint and moxibustion. Both groups were treated for four weeks. Before and after the treatment
the spleen and kidney yang deficiency and water retention symptoms were scored.The liver function was evaluated by Child-Pugh.The levels of glutamic-pyruvic transaminase (ALT)
glutamic oxalacetic transaminase (AST)
total bilirubin (TBIL) and serum albumin (ALB) were detected.Ascites was detected by B ultrasonic.And weight and abdominal perimeter were measured. Result: According to Ridit analysis
the clinical effect in the observation group was higher than that in the control group (P <0.05).The effect in TCM syndromes in the observation group was also higher than that in the control group. After the treatment
the levels of ALT
AST and TBIL in the observation group were lower than that in the control group (P <0.05 or P <0.01)
but with no statistical significance in the ALB level in the inter-group comparison.The observation group showed higher spleen and kidney yang deficiency and Child-Pugh scores (P <0.01) and 24-hour urine volume (P <0.01) but lower weight and abdominal perimeter than that in the control group (P <0.05). Conclusion: Based on the conventional western medicine therapy
the comprehensive traditional Chinese medicine therapy can ameliorate the function of patients with hepatocirrhosis ascites (spleen and kidney Yang deficiency and water retention symptoms)
relieve clinical symptoms and signs and promote the ascites regression
with superior comprehensive efficacy comprehensive traditional Chinese medicine syndrome score than the pure western medicine therapy.