FENG Qing-tao. Shengui Yixin Decoction on Patients with Chronic Heart Failure and Its Effect on Cardiac Ultrasound Index[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(17): 165-168.
DOI:
FENG Qing-tao. Shengui Yixin Decoction on Patients with Chronic Heart Failure and Its Effect on Cardiac Ultrasound Index[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(17): 165-168. DOI: 10.13422/j.cnki.syfjx.2015170165.
Shengui Yixin Decoction on Patients with Chronic Heart Failure and Its Effect on Cardiac Ultrasound Index
Objective: To study the clinical effect of Shengui Yixin decoction on patients with chronic heart failure and its effect on cardiac ultrasound index. Method: Totally one hundred and twenty-four cases of heart failure patients were divided randomly into the control group (n=50) and the treatment group (n=74) according to the odevity of their admission time. The control group received the therapies of removing inducing factors
adjusting lifestyle
providing psychological intervention for those with anxiety and depression and taking drugs
digoxin. The treatment group was given Shengui Yixin decoction for 4 weeks
4 tablets/time
3 times/day
with 2 weeks in 1 courses of treatment
in addition to the therapies of the control group. The therapeutic effect was evaluated by Lee's heart failure score
the N terminus natriuretic peptide (NT-proBNP)
cardiac troponin (cTn) and galectin-3 were observed. The life quality was evaluated by the 36-item short form health questionnaire (SF-36) and the Minnesota living with heart failure quality scale (MLHFQ). The patients' cardiac output (CO)
stroke volume (SV)
left ventricular ejection fraction (LVEF)
left ventricular end diastolic diameterleft (LVDD) and cardiac index (CI) were detected by ultrasound. Result: After the four-week treatment
the efficacy of the treatment group was significant statistically compared with the control group (P<0.05). The total effective rate of the treatment group was significant statistically compared with the control group (P<0.05). NT-proBNP
cTn
galectin-3 and Lee score in the control group were significant statistically compared with that before the treatment (P<0.05). NT-proBNP
cTn
galectin-3 and Lee's score in the treatment group after the treatment were significant statistically compared with the control group before the treatment (P<0.05). SV
CO
LVEF
LVDD
CI in the control group were significant statistically compared with that before the treatment (P<0.05). SV
CO
LVEF
LVDD
CI in the treatment group after the treatment were significant statistically compared with the control group before the treatment (P<0.05). Conclusion: Shengui Yixin decoction can be used to treat chronic congestive heart failure (heart function grade Ⅱ-Ⅲ) caused by coronary heart disease and hypertensive heart disease
improve the quality of life
enhance myocardial contractility
reduce myocardial cell damage and delay ventricular reconstruction.
Effect of Method of Regulating Qi to Dissipate Blood Stasis and Phlegm on Cardiac Rehabilitation in Patients with Qi Deficiency and Blood Stasis Type Chronic Heart Failure
Effect of Shengui Yixin Decoction on Toll-like Receptors 4/Nuclear Factor Kappa B in Patients with Chronic Heart Failure
Wenshen Huoxue Decoction in Ameliorating Activity Tolerance of Patients with Senile Chronic Heart Failure and Yang Blood Stasis
Effect of Qihong Jieyu Decoction Treatment on 60 Patients with Depression Secondary to Chronic Heart Failure
Analysis of Animal Model of Chronic Heart Failure Based on Combination of Diseases and Syndromes of Traditional Chinese Medicine and Western Medicine
Related Author
Hai-ping MOU
Ting LIU
Hong-bo MA
FENG Qin-tao
YANG Jing
ZHANG Yan
LYU Shang-zeng
MIAO Hua-wei
Related Institution
Ji'nan Huaiyin People's Hospital
Shandong Provincial Hospital
Liaoning University of Chinese Medicine
The Second Affiliated Hospital of Liaoning University of Chinese Medicine
The Affiliated Hospital of Changchun University of Chinese Medicine