Effect of Tianning Decoction in Treating 32 Cases with Migraine

CHEN Wei; YANG Xue-shan; LIU Zong-tao

doi:10.13422/j.cnki.syfjx.2015170173

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Effect of Tianning Decoction in Treating 32 Cases with Migraine

更新时间：2024-01-04

- Effect of Tianning Decoction in Treating 32 Cases with Migraine
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 21, Issue 17, Pages: 173-176(2015)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2015170173
  CLC： R277.7
- Published：2015
- 稿件说明：
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CHEN Wei, YANG Xue-shan, LIU Zong-tao. Effect of Tianning Decoction in Treating 32 Cases with Migraine[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(17): 173-176.
DOI：

CHEN Wei, YANG Xue-shan, LIU Zong-tao. Effect of Tianning Decoction in Treating 32 Cases with Migraine[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(17): 173-176. DOI： 10.13422/j.cnki.syfjx.2015170173.

摘要

目的: 观察天宁方治疗阴虚阳亢型偏头痛的临床疗效及评价其安全性。方法: 采用随机对照研究

将符合纳入标准的阴虚阳亢型偏头痛64例患者分为治疗组(天宁方组)和对照组各32例;对照组给予盐酸氟桂利嗪胶囊治疗

治疗组则给予天宁方进行治疗

两组均连续给药8周。评定临床疗效

观测头痛指数评分、中医证候积分等变化。结果: 治疗后治疗组临床总有效率93.8%

对照组为84.3%

治疗组明显优于对照组(P<0.05);两组治疗后与治疗前头痛发作次数及头痛天数评分比较

组内比较差异有统计学意义(P<0.05

P<0.01)

治疗8周后两组间评分比较有统计学意义(P<0.05);两组患者头痛指数评分治疗后与治疗前组内比较

均有不同程度下降(P<0.05

P<0.01)

两组治疗后组间比较

治疗组优于对照组(P<0.05);两组患者中医证候积分治疗后均有不同程度的下降

以治疗组下降更为明显(P<0.01)

而对照组虽有下降但无统计学意义;两组间治疗后比较治疗组优于对照组(P<0.05);两组治疗后伴随症状积分比治疗前均有所改善

差异有统计学意义(P<0.05

P<0.01)

两组间比较

部分伴随症状(恶心、呕吐、畏光)治疗组优于对照组(P<0.05)。结论: 天宁方治疗偏头痛临床疗效肯定

且明显优于西药盐酸氟桂利嗪胶囊

是一种安全有效的治疗偏头痛药物。

Abstract

Objective: To observe the clinical efficacy and safety of Tianning decoction in the treatment of migraine with Yin defieiency and Yang hyperativity syndrome. Method: Altogether 64 eligible migraine patients with Yin defieiency and Yang hyperativity syndrome were randomly divided into the treatment group (Tianning decoction group) and the control group (Flunarizine group). Each group included 32 patients and continuously treated for 8 weeks. The clinical efficacy was evaluated on the basis of the headache index score and the change in the traditional Chinese medicine (TCM) syndrome score. Result: After the treatment

the total effective rate of the treatment group was 93.8%

and that of the control group was 84.3%

indicating an obvious superiority between them (P<0.05). The intra-group comparison in the headache attack frequency and headache days score between the two groups before and after the treatment showed differences with statistical significance (P<0.05

P<0.01). After 8 weeks of the treatment

the inter-group comparison in scores between the two groups showed statistical significance (P<0.05). The inter-group comparison in the headache score between the two groups before and after the treatment decreased to varying degrees (P<0.05

P<0.01)

with an obvious superiority in the treatment group to the control group (P<0.05). The TCM symptom score of the treatment group was significantly lower than that of the control group after the treatment (P<0.05).The score of the control group also decreased

but with no statistical significance. The inter-group comparison showed a superiority in the treatment group to the control group after the treatment (P<0.05). The accompanying symptoms (nausea

vomiting

photophobia

tears) were relieved in both groups after the treatment

with statistical significance in difference (P<0.05

P<0.01).And the treatment group was superior to the control group in some accompanying symptoms (P<0.05). Conclusion: The clinical efficacy of Tianning decoction is obviously superior to western medicine Flunarizine

and so can be used as a safe and effective drug for migraine.

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Related Institution

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