Objective: To investigate the clinical effect of Baiji Kanglao gel combined with chemotherapeutic drugs on cavitary pulmonary tuberculosis and extra pulmonary tuberculosis. Method: Totally eighty-seven cases of cavitary pulmonary tuberculosis and extra pulmonary tuberculosis treated in our hospital from January 2011 to January 2013 were divided randomly into the research group (44 cases) and the control group (43 cases) according the visiting sequence. Both groups were treated with standard chemotherapy regimen of 3DLZVATH/15DLVTH. In addition to the chemotherapy

the research group was treated by Baiji Kanglao gel. The differences in the sputum negative conversion rate and lesion cure rate between both groups after being treated for 3

12 and 18 months were compared. Result: The sputum negative conversion rates of the research group after being treated for 3

12 and 18 months were 47.73%

75.00% and 84.09% respectively

which were higher than the control group (27.91%

51.16% and 60.47%). The significant differences were only found in the 12th and 18th months (P<0.05). The lesion effective rate and the cavity effective rate of the research group in the 12th and 18th months were significantly higher than that of the control group (P<0.05). There was no significant difference in fever

expectoration

cough and hemoptysis between the two groups before the treatment

but with significant lower values in the research group than the control group after the treatment (P<0.05). The total effective rate in the research group was 95.45%

which was significantly higher than 70.07% in the control group (P<0.05). Conclusion: Baiji Kanglao gel combined with conventional chemotherapeutic drugs has a significant effect in treating cavitary pulmonary tuberculosis and extra pulmonary tuberculosis by enhancing the tuberculosis negative conversion rate

relieving clinical symptom of patients and increasing the treatment effect.