WANG Zhi-ming, LIU Jiu-shi, GUO Yao-jie, et al. Distribution of Lignans in Different Parts of Schisandrae Chinensis Fructus[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(18): 35-39.
DOI:
WANG Zhi-ming, LIU Jiu-shi, GUO Yao-jie, et al. Distribution of Lignans in Different Parts of Schisandrae Chinensis Fructus[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(18): 35-39. DOI: 10.13422/j.cnki.syfjx.2015180035.
Distribution of Lignans in Different Parts of Schisandrae Chinensis Fructus
Objective: To establish a method for determination of ten lignans in Schisandrae Chinensis Fructus
and analyze difference of contents of ten lignans in the pulp
seed shell and seed kernel of Schisandrae Chinensis Fructus for researching regularities of their distribution. Method: HPLC was developed for determination of schisandrol A
gomisin D
gomisin J
schisandrol B
angeloylgomisin H
gomisin G
schisantherin A
schisandrin A
schisandrin B and schisandrin C in Schisandrae Chinensis Fructus from different area
mobile phase consisted of acetonitrile-water for gradient elution
detection wavelength was set at 220 nm and injection volume was 4 μL. Result: The content of total lignans in the seed kernel
seed shell and pulp of Schisandrae Chinensis Fructus from different area were 30.08
9.76
2.24 mg· g-1
respectively.Contents of ten lignans in these three parts of Schisandrae Chinensis Fructus showed significant difference
which decreased in the order of the seed kernel> the seed shell> the pulp. Conclusion: The developed method displays distribution information of lignans in three parts of Schisandrae Chinensis Fructus well
which can provide a reference for clinical application of Schisandrae Chinensis Fructus.