XU Yu-ling, LIANG Yue, ZHAO Qun, et al. Optimization Preparation Process of Salviae Miltiorrhizae Radix et Rhizoma Extract in mass production[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(19): 24-27.
DOI:
XU Yu-ling, LIANG Yue, ZHAO Qun, et al. Optimization Preparation Process of Salviae Miltiorrhizae Radix et Rhizoma Extract in mass production[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(19): 24-27. DOI: 10.13422/j.cnki.syfjx.2015190024.
Optimization Preparation Process of Salviae Miltiorrhizae Radix et Rhizoma Extract in mass production
Objective: To discuss preparation process parameters of Salviae Miltiorrhizae Radix et Rhizoma extract in mass production. Method: Single factor tests were adopted
pretreatment of raw materials of tanshinone extract was investigated by taking contents of cryptotanshinone and tanshinone ⅡA as indicators.Water extraction temperature of Salviae Miltiorrhizae Radix et Rhizoma was optimized by taking solid-containing content and the content of salvianolic acid B as indexes.With solid-containing content
the content of salvianolic acid B and fingerprints as indicators
raw materials of water extraction for Salviae Miltiorrhizae Radix et Rhizoma were determined.Fingerprints was employed to determine optimum concentration temperature of water extract of Salviae Miltiorrhizae Radix et Rhizoma. Result: Pretreatment of raw materials of tanshinone extract was cutting into small pieces of 1-2 cm.Raw materials of total phenolic acid extract in Salviae Miltiorrhizae Radix et Rhizoma can use the residues of tanshinone extract
extraction temperature was revised to 100℃
the concentrated temperature was revised to 80℃. Conclusion: These optimized process conditions are stable and feasible
which can provide experimental basis for large-scale production of Salviae Miltiorrhizae Radix et Rhizoma extract.