ZHANG Shi-chuan, LI Ya-nan, WEI Xue-xian, et al. Anti-bacterial Effects of Ingredients of Jingwanhong Prescription Against [J]. Chinese journal of experimental traditional medical formulae, 2015, 21(19): 111-115.
DOI:
ZHANG Shi-chuan, LI Ya-nan, WEI Xue-xian, et al. Anti-bacterial Effects of Ingredients of Jingwanhong Prescription Against [J]. Chinese journal of experimental traditional medical formulae, 2015, 21(19): 111-115. DOI: 10.13422/j.cnki.syfjx.2015190111.
Anti-bacterial Effects of Ingredients of Jingwanhong Prescription Against
Objective: To study the effect of anti-Candida albicans of Jingwanhong constituents of berberine hydrochloride
baicalin and borneol in vitro. Method: The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of berberine hydrochloride
baicalin
borneol (50
100
150 g·L-1) were determined by two-fold dilution method and checkboard method. The anti-bacterial effects of the combined three drugs were measured and the combined inhibitory fraction (FIC) was calculated. Result: The MIC of berberine hydrochloride
baicalin
borneol was 160
1 280
320 mg·L-1
and the MBC was 640
20 480
640 mg·L-1
respectively. Baicalin and berberine hydrochloride combined showed the synergistic effect with FIC index of 0.5.The FIC of baicalin and borneol combined was 0.625
which showed the additive effect.The berberine hydrochloride and borneol combined showed the synergistic effect with FIC index was 0.5.Three-drug combination had a certain synergy with the FIC index of 0.375. Conclusion: Three constituents of berberine hydrochloride
baicalin
borneol could inhibit C. albicans
and three drugs combined showed a certain synergy.
Determination of Berberine Hydrochloride,Baicalin and Wogonin in Yankening Pian by HPLC
Simultaneous Determination of Puerarin, Liquiritin, Baicalin and Berberine Hydrochloride in Gegenqinlian Micropills by RP-HPLC
Anti-bacterial Synergistic Effects of Baicalin and Borneol on
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