Objective: To evaluate the curative effect of Juanbi Zhitong decoction by orally taking and fumigation on gonarthromeningitis according to Chinese and western medicine scheme. Method: One hundred and twenty-two patients were randomly divided into control group (62 cases) and observation group (60 cases) by random number table. Patients in control group received joint puncture and triamcinolone acetonide injection and hyaluronic acid sodium injection each for 20 mL after arthroedema was pumped

1 time/7 days

for totally 2 times

and patients also orally took celecoxib capsules

0.2 g/time

1 time/day. Based on the treatment of control group

patients in observation group received additional Juanbi Zhitong decoction by orally taking and fumigation. Course of treatment was 4 weeks in both groups. Before and after treatment

scores of pain

swell and joint motion

as well as pain remission and disappearing time were recorded. Scores of Bristol knee-joint were graded

and levels of erythrocyte sedimentation rate (ESR) and C-reaction protein (CRP) were detected both before and after treatment. Result: Ridit analysis showed that the clinical effect in observation group was superior to that in control group

with significantly statistical difference (P<0.05). Scores of pain

swelling and joint motion in observation group were lower than those in control group (P<0.01). Average remission and disappearing time of pain in observation group was shorter than that in control group (P<0.05). Levels of ESR and CRP were lower than those in control group (P<0.05). After treatment

compared with the data before treatment

various dimensional scores of Bristol knee-joint and total scores increased obviously (P<0.01)

and those scores in observation group were higher than the data in control group except the score of malformation (P<0.05

P<0.01). And excellent and good rate in observation group was 70% higher than 51.2% in control group (P<0.05). Conclusion: Juanbi Zhitong decoction by orally taking and fumigation combined with western medicine can relive symptoms of pain and swell

promote the recovery of joint function and improve quality in the treatment of gonarthromeningitis. It has a good effect in Chinese and western medicine scheme.