TIAN Zi-you, CHEN Sai-zhen, XU Li-jun, et al. Edaravone Combined with Danhong Injection in Treating Acute Cerebral Infarction[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(20): 218-224.
DOI:
TIAN Zi-you, CHEN Sai-zhen, XU Li-jun, et al. Edaravone Combined with Danhong Injection in Treating Acute Cerebral Infarction[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(20): 218-224. DOI: 10.13422/j.cnki.syfjx.2015200218.
Edaravone Combined with Danhong Injection in Treating Acute Cerebral Infarction
Objective: To assess the effect and safety of edaravone combined with Danhong injection in treating acute cerebral infarction (ACI) by Meta-analysis. Method: Randomized control trials (RCTs) of edaravone combined with Danhong injection in treating ACI were retrieved from Cochrane Library
PubMed
MedLine
ScienceDirect
CNKI
Wanfang and VIP (from January 2000 to December 2014). The data was analyzed by using RevMan 5.1. Result: Twenty-five RCTs were included. The results showed that edaravone combined with Danhong injection had statistically significant differences compared with control group in the effective rate for ACI [OR=4.15
95%CI (3.24
5.21)]
the neurological deficit scores [WMD=-3.75
95%CI (-4.53
-2.96)] and the activities of daily living score [WMD=14.40
95%CI (12.97
15.83)]. Conclusion: Compared with edaravone treatment group
Danhong injection treatment group and routine treatment group
edaravone combined with Danhong injection has a better efficacy for ACI.
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ZHANG Hui
QIU Bo
ZHANG Jing
ZHANG Wei
PAN Yun-zhi
LIU Hong-bin
SUN Xing-yuan
WANG Shu
Related Institution
Forth Department of Neurology,Third Affiliated Hospital of Qiqihar MedicalCollege
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Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences