WANG Rong, HU Rong-feng, DING Ling-zhen, et al. Investigation of Preparation Technology of Gastrodin Phospholipid Complex[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(21): 14-16.
DOI:
WANG Rong, HU Rong-feng, DING Ling-zhen, et al. Investigation of Preparation Technology of Gastrodin Phospholipid Complex[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(21): 14-16. DOI: 10.13422/j.cnki.syfjx.2015210014.
Investigation of Preparation Technology of Gastrodin Phospholipid Complex
Objective: To optimize conditions for formation of gastrodin phospholipid complex. Method: The complex was prepared by solvent evaporation method.Taking binding rate of gastrodin and soybean phospholipid as index
effects of reaction solvent type
ratio of gastrodin to phospholipid
reactive temperature
reactive time and the concentration of reactant on preparation technology were studied by single factor tests and orthogonal design. Result: Optimum preparation conditions of gastrodin phospholipid complex were obtained as follows:tetrahydrofuran as reaction solvent
gastrodin-soybean phospholipid (1: 2)
reaction temperature at 40 ℃
reaction time of 0.5 h
the concentration of gastrodin 20 g·L-1
speed of 100 r·min-1.Binding rate of the complex was up to 98.3%. Conclusion: Optimized preparation technology in this research is stable and feasible
it can provide conditions for further study of gastrodin.
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Related Institution
State Key Laboratory of Efficacy and Utilization of Medicinal Plants,Guizhou Medical University
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