Objective: To explore the pair medication rules of Professor SHAN Zhao-wei in treating bile reflux gastritis (BRG). Method: Medcase V 3.2 data mining system was used to record all clinical cases that were diagnosed and treated by Prof. SHAN Zhao-wei in 2011-2013 in a real-time manner

and build a database of Professor SHAN's clinical cases. The database was searched in multiple dimensions by taking ‘BRG’ as the key word

with the related data retrieved as a secondary disease database;pair medication for BRG was then analyzed according to the secondary database. Result: In the operational environment

if setting the standard for the listed parameters [Support=0.40

Confidence=0.87]

then 12 rule sets of items would be produced totally. According to binomial distribution of item sets content

they were divided into 6 groups. The pair medications whose support rate was more than 0.50 included Coicis Semen-Agrimoniae Herba

Coicis Semen-Atractylodis Macrocephalae Rhizoma

Agrimoniae Herba-Atractylodis Macrocephalae Rhizoma

Pseudostellariae Radix-Atractylodis Macrocephalae Rhizoma

Pseudostellariae Radix-Agrimonia pilosa

Pseudostellariae Radix-Coicis Semen. Conclusion: Prof. SHAN Zhao-wei commonly uses 6 groups of pair herbals in treating BRG. The treatment methods are mainly to invigorate spleen and supplement qi or invigorate spleen to eliminate dampness

reflecting the academic idea of Menghe Medicine to protect middle burner

spleen and stomach.