WANG Chao, LIU Chun-fang, LIN Na. Mechanism Progress of Traditional Chinese Medicine in Alleviating Hyperalgesia of Neuropathic Pain[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(22): 34-39.
DOI:
WANG Chao, LIU Chun-fang, LIN Na. Mechanism Progress of Traditional Chinese Medicine in Alleviating Hyperalgesia of Neuropathic Pain[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(22): 34-39. DOI: 10.13422/j.cnki.syfjx.2015220034.
Mechanism Progress of Traditional Chinese Medicine in Alleviating Hyperalgesia of Neuropathic Pain
In conjunction with the title search and MeSH retrieval from CNKI
Pubmed
Web of science and other databases
we screened literature mentioned mechanisms of neuropathic pain(NP) for Chinese medicine intervention in the past 20 years. By Summarizing and analysising the literature
70 articles were selected
and the main aspects that mentioned for NP treatment with Chinese medicine are as following:descending inhibition/facilitation systems
ion channels
membrane receptors
neuroinflammation
glial cell activation
signaling pathways
antiapoptotic
antioxidative stress
enzyme activity inhibition
et al. Collectively
Chinese medicine treatment for NP hyperalgesia are effective
with characteristics of multitargets intervention
not only by inhibiting nerve impulses
Chinese medicine can also improve NP neurogenic inflammation
Chinese medicine intervention for NP neuroinflammation gradually attracted scholars' attention
Identification of Pharmacodynamic Material Basis of Ruyi Zhenbaowan by Multidimensional Correlation Model of "Pharmacodynamic-target-component-pharmacokinetic"
Analgesic Effect and Mechanism of Osteoking on Dorsal Root Ganglion Compression Model Rats
Traditional Chinese Medicine Diagnosis and Treatment of Neuropathic Pain from Theory of Chronic Pain Entering Collaterals
Dihydroartemisinin Regulates Neuro-microglia to Relieve Neuropathic Pain
Mechanism of Honghua Oral Liquid in Alleviating Neuropathic Pain
Related Author
XU Mingzhu
LI Huaiping
MA Zhaochen
LI Tao
LIU Yudong
XIAO Ziqing
ZHANG Chu
CHEN Kedian
Related Institution
College of Traditional Chinese Medicine(TCM), Yunnan University of Chinese Medicine
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences