WU Jia-rui, WANG Kai-huan, JI Kai, et al. Medication Rules for Treating Diabetes Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(22): 214-217.
DOI:
WU Jia-rui, WANG Kai-huan, JI Kai, et al. Medication Rules for Treating Diabetes Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(22): 214-217. DOI: 10.13422/j.cnki.syfjx.2015220214.
Medication Rules for Treating Diabetes Based on Data Mining
Objective: To explore the medication rules of traditional Chinese medicine for treating diabetes. Method: The traditional Chinese medicine (TCM) prescriptions for treating diabetes were collected to build a database based on TCM inheritance assist system. Association rules algorithm and entropy clustering methods were used to determine the frequency of single drug and drug combinations
the association rules between drugs
core drug combinations and so on. Result: Based on the analysis of prescriptions for treating diabetes
the frequently adopted drugs were Astragali Radix
Poria
Rehmanniae Radix
Dioscoreae Rhizoma
and Salviae Miltiorrhizae Radix et Rhizoma. The frequently adopted drug combinations were 'Salviae Miltiorrhizae Radix et Rhizoma and Astragali Radix'
'Astragali Radix and Rehmanniae Radix'
and 'Poria and Astragali Radix'. In the association rules with a confidence of over 0.85
the drug combinations included 'Corni Fructus
Moutan Cortex
Poria->Dioscoreae Rhizoma'
'Moutan Cortex
Alismatis Rhizoma
Poria->Dioscoreae Rhizoma'
and 'Dioscoreae Rhizoma
Moutan Cortex
Alismatis Rhizoma->Poria'. Conclusion: In TCM
the drugs used for treating diabetes mostly have the effects of tonifying Qi and Yin
strengthening spleen and kidney
clearing heat and promoting fluid
and activating circulation to remove blood stasis
which reflects a refined and rational compatibility.
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Related Author
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Ya-dong LIN
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Related Institution
Xiyuan Clinical Medical College, Beijing University of Chinese Medicine
Beijing Key Laboratory of Pharmacology of Chinese Materia Medica,Institute of Basic Medical Sciences,Xiyuan Hospital,China Academy of Chinese Medical Sciences
Institute of Information on Traditional Chinese Medicine,China Academy of Chinese Medical Sciences
Shandong Academy of Chinese Medicine
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