SONG Jing-mei, WU Jia-rui, JIANG Di, et al. Medication Rules of Prescriptions of Hepatopathy Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(22): 218-221.
DOI:
SONG Jing-mei, WU Jia-rui, JIANG Di, et al. Medication Rules of Prescriptions of Hepatopathy Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(22): 218-221. DOI: 10.13422/j.cnki.syfjx.2015220218.
Medication Rules of Prescriptions of Hepatopathy Based on Data Mining
Objective: To investigate the medication rules of traditional Chinese medicines(TCM) for the treatment of hepatopathy by National Medical Masters. Method: The prescriptions for hepatopathy were collected to build a database based on TCM inheritance assist system. Apriori algorithm and complex system entropy cluster were adopted to determined the frequency of single medicine and drug combinations that used in prescriptions
and the association rules between drugs e. Result: Frequently used herbs included Poria
Salviae Miltiorrhizae Radix et Rhizoma
Artemisiae Scopariae Herba
Atractylodis Macrocephalae Rhizoma and Bupleuri Radix;Frequently used drug combinations included 'Salviae Miltiorrhizae Radix et Rhizoma and Poria'
'Atractylodis Macrocephalae Rhizoma and Poria' and 'Salviae Miltiorrhizae Radix et Rhizoma and and Paeoniae Radix Rubra'.The association rules with a confidence of above 0.6 included 'Astragali Radix-> Salviae Miltiorrhizae Radix et Rhizoma and'
'Atractylodis Macrocephalae Rhizoma-> Poria'
'Astragali Radix-> Poria' and 'Pilosula Codonopsis-> Poria'. Conclusion: The prescriptions used for the treatment of hepatopathy mostly have the effects of reinforcing spleen and eliminating dampness
cooling blood and activating blood circulation
nourishing Yin to calm liver and discharging liver and relieving depression
with the refined compatibility and the TCM medication principles for treating symptoms and root causes.
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Related Author
ZHANG Bing
YANG Bing
CHEN Dan
GUO Wei-xian
WU Jia-rui
ZOU Jin
YANG Xue-qin
ZHANG Xiao-yong
Related Institution
Xiyuan Clinical Medical College, Beijing University of Chinese Medicine
Beijing Key Laboratory of Pharmacology of Chinese Materia Medica,Institute of Basic Medical Sciences,Xiyuan Hospital,China Academy of Chinese Medical Sciences
Institute of Information on Traditional Chinese Medicine,China Academy of Chinese Medical Sciences
Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM), Ministry of Education, College of Computer Science, School of Pharmacy, Jiangxi University of TCM
Graduate School, Hebei University of Chinese Medicine