ZHOU Li, WANG Yong-zhong, GAO Jia-rong, et al. Determination of Three Anthraquinones from Rhei Radix et Rhizoma in Huangxiong Kangshuan Capsules Before and After Compatibility[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(23): 25-27.
DOI:
ZHOU Li, WANG Yong-zhong, GAO Jia-rong, et al. Determination of Three Anthraquinones from Rhei Radix et Rhizoma in Huangxiong Kangshuan Capsules Before and After Compatibility[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(23): 25-27. DOI: 10.13422/j.cnki.syfjx.2015230025.
Determination of Three Anthraquinones from Rhei Radix et Rhizoma in Huangxiong Kangshuan Capsules Before and After Compatibility
Objective: To observe contents variation of emodin
chrysophanol and physcion from Rhei Radix et Rhizoma in Huangxiong Kangshuan capsules before and after compatibility. Method: According to prescription
herbs were extracted separately in different proportion and separate extraction were combined partly.Contents of emodin
chrysophanol and physcion were determined by UPLC. Result: Contents of emodin
chrysophanol and physcion increased significantly when herbs extracting separately
which reached to 2.437
17.040
2.720 mg·g-1
respectively;then declined to 1.914
13.236
2.155 mg·g-1 in combined samples;decreased significantly when herbs extracting together
which reached to 1.308
6.478
1.169 mg·g-1
respectively. Conclusion: Great influence of combination of Rhei Radix et Rhizoma with other herbs in this prescription on contents of main chemical constituents is mainly carried on in extraction process of Huangxiong Kangshuan capsules.
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Related Author
XUE Xiao-ping
LU Yan-min
WANG Qian
LIU Hong-bin
LI Xin-jian
FANG Cui-fen
ZHU Ming
WANG Qiang
Related Institution
Zhejiang Chinese Medical University
Zhejiang Institute for Food and Drug Contrl
Tian Jin Nan Kai Hospital
Key Laboratory of Digital Quality Evaluation Technology of Chinese Materia Medica, State Administration of Traditional Chinese Medicine(TCM), Engineering Technology Research Center for Chinese Materia Medica Quality of Universities in Guangdong Province, School of TCM, Guangdong Pharmaceutical University