ZHANG Min, ZHU Wei-feng, JI Qin, et al. Research Progress of DNA Demethylation of Anti-tumor Traditional Chinese Medicines[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(23): 224-229.
DOI:
ZHANG Min, ZHU Wei-feng, JI Qin, et al. Research Progress of DNA Demethylation of Anti-tumor Traditional Chinese Medicines[J]. Chinese journal of experimental traditional medical formulae, 2015, 21(23): 224-229. DOI: 10.13422/j.cnki.syfjx.2015230224.
Research Progress of DNA Demethylation of Anti-tumor Traditional Chinese Medicines
High methylation of DNA is closely related to occurrence of tumor.Reversing aberrant methylation of DNA of tumor cells
restoring expression of tumor suppressor gene or DNA repair gene become new hot spots in development and research of anti-tumor drugs.Compared to single target point and resistance of chemical drugs
traditional Chinese medicine (TCM) has advantages of comprehensive and multiple targets for treatment.However
there are few reports on effect of TCM on DNA demethylation.In this paper
anti-tumor TCM and composition in TCM on DNA demethylation are combed.All these TCM were classified into four types based on their efficacy
including heat-clearing
activating blood circulation to remove stasis
anti-rheumatism and others.Demethylation effects of these Chinese herbs on different target genes in different tumors were described
Anti-tumor Mechanism of Traditional Chinese Medicine with Effect of Softening Hardness and Dissipating Mass: A Review
Investigation of Host-guest Complexation Between 4-Sulfonylcalix [6] Arene and 15 Alkaloids from Traditional Chinese Medicines and Inhibitory Effect of Binding System on Proliferation of HepG2 and H9c2 Cells
11 Kinds of Signal Pathways in Anti-tumor Mechanism of Traditional Chinese Medicine
Prevention and Treatment of Colorectal Cancer Through Traditional Chinese Medicine Targeted Wnt Signaling Pathway: A Review
Regulation of Ferroptosis by Traditional Chinese Medicine for Colorectal Cancer Intervention: A Review
Related Author
HU Yue
WANG Linfeng
LI Yue
LIU Rui
HUA Baojin
Jia-yang LI
Xuan YU
Zhen-yu ZHOU
Related Institution
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Graduate School,Beijing University of Chinese Medicine
State Key Laboratory of Component-based Chinese Medicine, Institute of Traditional Chinese Medicine (TCM),Tianjin University of TCM
Shaanxi University of Chinese Medicine
The Affiliated Hospital of Shaanxi University of Chinese Medicine