Explore Differences in Coptidis Rhizome Processed with Different Ginger Juice by Tongue Scanning Electron Microscopy in Rats

DENG Yu-fen; ZHONG Ling-yun

doi:10.13422/j.cnki.syfjx.2016010006

您当前的位置：

首页 >

文章列表页 >

Explore Differences in Coptidis Rhizome Processed with Different Ginger Juice by Tongue Scanning Electron Microscopy in Rats

更新时间：2024-01-04

- Explore Differences in Coptidis Rhizome Processed with Different Ginger Juice by Tongue Scanning Electron Microscopy in Rats
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 22, Issue 1, Pages: 6-9(2016)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2016010006
  CLC： R285.5
- Published：2016
- 稿件说明：
移动端阅览
DENG Yu-fen, ZHONG Ling-yun. Explore Differences in Coptidis Rhizome Processed with Different Ginger Juice by Tongue Scanning Electron Microscopy in Rats[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 6-9.
DOI：

DENG Yu-fen, ZHONG Ling-yun. Explore Differences in Coptidis Rhizome Processed with Different Ginger Juice by Tongue Scanning Electron Microscopy in Rats[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 6-9. DOI： 10.13422/j.cnki.syfjx.2016010006.

摘要

目的: 通过SD大鼠舌象扫描电镜超微结构观察不同姜汁炮制黄连药性差异性变化。方法: 将大鼠随机分为正常组、生黄连组、鲜姜制黄连组、干姜制黄连组、鲜姜汁组、干姜汁组

分别灌服相应水煎液3个星期

沿大鼠舌根剪下舌头

按常规扫描电镜样本处理

然后通过扫描电镜观察各组大鼠舌象超微结构。结果: 与正常组比较

生黄组、鲜姜黄连、干姜黄连在数值降低上存在极显著性差异(P<0.01)。且大鼠舌象覃状乳突和丝状乳突的角质化及剥落程度不及正常组明显。干姜汁组在数值上升上具有显著性差异(P<0.05)

丝状乳突和覃状乳突的剥落及角质化程度也是最明显的。与生黄连组比

鲜姜黄连、干姜黄连组在数值上升上存在显著性差异(P<0.05)

干姜组、鲜姜组在数值上升上存在极显著性差异(P<0.01)。覃状乳突和丝状乳突的角质化及剥落程度明显。与鲜姜制黄连比较

干姜黄连组丝状乳突数值存在上升趋势

且乳突剥落及角质化程度更明显。与干姜汁组比较

鲜姜汁组丝状乳突存在数值降低的趋势

且乳突剥落及角质化程度不及干姜汁明显。结论: 姜制黄连与生黄连组的大鼠舌象显微结构存在显著性差异

其结果提示

黄连经姜制后寒性得到缓和

符合中医理论中的"从制"理论

且药性寒热的变化可以通过舌象扫描电镜的显微结构得以体现。同时

干姜的热性强与鲜姜也能通过大鼠舌象变化得以体现。为姜制黄连的炮制机制研究奠定了基础。

Abstract

Objective: Through to observe the medicinal difference changes in Coptidis Rhizome(CR) processed by different ginger juice through ultrastructural tongue scanning electron microscopy(SEM) in SD rats. Method: The rats were randomly divided into normal group

raw CR group

CR processed by fresh ginger group(FGRC)

RC processed by dried ginger group(RCDG)

fresh ginger juice group(FG) and dry ginger group(DG)

respectively took corresponding solution for three weeks. Their tongues were cut off along tongue roots

and processed according to the conventional SEM sample methods

and their ultrastructure was observed by SEM. Result: Compared with the normal group

there was extremely significant differences in numerical lowering between CR group

FGRC group and DGRC group(P<0.01). Keratinization and spalling degree of tain mastoid and filamentous mastoid were not as obvious as normal group. DG group had significant difference in the value increase(P<0.05)

and their spalling and keratinization of filamentous mastoid and tain mastoid were also the most obvious. Compared with CR group

there was significant difference in value increase in FGRC group and DGRC group(P<0.05). There was extremely significant difference in value increase in DG group and FG group(P<0.01)

and the keratinization and spalling degree of tain mastoid and filamentous mastoid were obvious. Compared with FGRC group

the value of filamentous mastoid was in a rise trend in DGRC

and its mastoid keratinization and spalling degree were more obvious. Compared with DG group

the value of filamentous mastoid was in a decline trend in FG group

and its mastoid spalling and keratinization degree were not so obvious. Conclusion: DGRC there was significant difference in tongue microstructure between CR processed by ginger groups and raw CR group. The results suggest that the cold property of CR can be relieved after processing with ginger

in line with the 'processing' theory of traditional Chinese medicine

and the changes in medicinal cold and hot properties can be reflected from the microstructure of tongue in SEM. At the same time

DG and FG have hot properties

which can be also reflected from the microstructure changes in SEM

laying a solid foundation for the processing mechanism of ginger-processed CR.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Mechanism of Action of Coptidis Rhizoma and Ophiopogonis Radix in Delaying Diabetic Nephropathy Based on EGFR/PI3K/Akt Signaling Pathway

Effect of Compatibility of Wujiwan on Pharmacokinetics and Tissue Distribution of Representative Components

Functions of Scutellariae Radix， Coptidis Rhizoma， and Phellodendri Chinensis Cortex in Materia Medica and Treatise on Febrile and Miscellaneous Diseases

Traditional Chinese Medicine Syndrome of Primary Sjögren's Syndrome Patients with Interstitial Lung Disease

Explanation of Scientific Connotation of Euodiae Fructus Stir-fried with Coptidis Rhizoma Based on UPLC-Q-TOF/MS and Pattern Recognition Technology

Related Author

LI Shaoyu

GONG Man

LI Qiufang

DAI Liping

WANG Guiqun

YANG Qiuchen

ZHANG Qiongqiong

XU Erping

Related Institution

Reproductive Health Hospital of the Third Affiliated Hospital of Zhengzhou University

School of Pharmacy， Henan University of Chinese Medicine

Academy of Chinese Medical Sciences， Henan University of Chinese Medicine

Henan Collaborative Innovation Center for Research and Development on the Whole Industry Chain of Yu-Yao，Henan University of Chinese Medicine

Wangjing Hospital， China Academy of Chinese Medical Sciences

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰