Nurmuhammat·, Muhammataly, Axim·, et al. Analyze and Discuss Prescription Rules in Treatment of Coronary Heart Disease Based on High-frequency Medicine and Efficacy Compatibility Data[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 200-206.
DOI:
Nurmuhammat·, Muhammataly, Axim·, et al. Analyze and Discuss Prescription Rules in Treatment of Coronary Heart Disease Based on High-frequency Medicine and Efficacy Compatibility Data[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 200-206. DOI: 10.13422/j.cnki.syfjx.2016010200.
Analyze and Discuss Prescription Rules in Treatment of Coronary Heart Disease Based on High-frequency Medicine and Efficacy Compatibility Data
Objective: To technically analyze the prescription rules in Uighur medical treatment of the coronary heart disease by means of Data mining for high-frequency medicine pairs and efficacy compatibility
reveal the inherent rules
explore the theory of prescription composition
guide proper clinical application
and provide prescriptions clues for new drug research and development. Method: With ancient prescriptions of physicians of past generations as the clue
and with the help of the modern data processing and statistical computer technology
the Microsoft Excel database of coronary heart disease(CHD) was established. By advanced filtering functions
statistical analysis was taken for the high-frequency herbal pairs and efficacy compatibility. Result: Known and unknown synergized and attenuatedherbal combinations were found through data mining and analysis
high-frequency herbal pairs included Anchusae Herba-Dracocephali Moldavicae Herba
Anchusae Herba-Serica Gluma/Rosa Rugosa Thunb
Anchusae Herba-Santali Albi Lignum.High-frequency 3-herbs groups included Anchusae Herba-Dracocephali Moldavicae Herba-Serica Gluma
Anchusae Herba-Serica Gluma-Santali Albi Lignum.High-frequency 4-herbs groups included Anchusae Herba-Dracocephali Moldavicae Herba-Serica Gluma-Santali Albi Lignum
Anchusae Herba-Dracocephali Moldavicae Herba-Succinum-Moschus.High-frequency 5-herbs groups included Serica Gluma-Margarita-Succinum/Moschus-Limonium Gmelinii-Centaurea Behen
Anchusae Herba-Dracocephali Moldavicae Herba-Serica Gluma/Margarita-Limonium Gmelinii-Centaurea Behen.The best combinations of efficacy compatibility were explored. Conclusion: The results suggest that cardiotonic drug was used as the main drug
with compatibility of brain tonifying
natural force boosting drug
tendon strengthening drug
kidney-reinforcing drug
stomach-invigorating drug and corresponding Munziq of Abnormal body fluids in the prescriptions for CHD
Basic prescriptions were constituted Serica Gluma
Santali Albi Lignum
Margarita
Moschus
Succinum
Limonium Gmelinii
Centaurea Behen
Silver Foil
Gold Foil
Croci Stigma
Anchusae Herba
Dracocephali Moldavicae Herba
Caryophylli Flos
Curcumae Radix
Doronicum Hookarii
and Bambusae Concretio Silicea.The deduction Provides a reference base for clinical making prescriptions and new drug research and development.