QIN Qing-xia, KONG Xiang-ying, LIN Na. Review of Effect of Tetramethylpyrazine on Neurogenesis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 219-223.
DOI:
QIN Qing-xia, KONG Xiang-ying, LIN Na. Review of Effect of Tetramethylpyrazine on Neurogenesis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(1): 219-223. DOI: 10.13422/j.cnki.syfjx.2016010219.
Review of Effect of Tetramethylpyrazine on Neurogenesis
but this effect is limited. Promoting neurogenesis by drugs is an important way for treatment of stroke. In recent years
tetramethylpyrazine(TMP) has received the attention because of its neuroprotection effect
and widely been applied in the prevention and treatment of cardiovascular and cerebrovascular diseases
especially stroke. The effect of TMP on neurogenesis after cerebral ischemia was accessed from Databases
such as Pubmed. In this article
we summarized
analyzed and reviewed the literature. The results showed that TMP significantly promoted neurogenesis by increasing the proliferation
differentiation
especially migration of neural stem cells after cerebral ischemia. This article summarized the possible mechanism of TMP in the prevention and treatment of stroke
also dprovide some useful hints for expand the application of TMP in other neurogenesis disorder related diseases.
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Related Author
YIN Jianing
ZHAO Xitong
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Related Institution
School of Chinese Materia,Beijing University of Chinese Medicine
Henan Key Laboratory for Modern Research on Zhongjing's Herbal Formulae,Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Chinese Medicine in Henan Province,Henan University of Chinese Medicine
Xiyuan Hospital, China Academy of Chinese Medical Sciences
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