Objective:To discuss the curative effect of Jiawei Yigong powder in treating diabetes gastroparesis(DGP) and its influence on plasma motilin and gastrin. Method:Ninety four patients were randomly divided into control group (46 cases) and observation group (48 cases). Patients in control group took mosapride citrate tablets

5 mg/time

3 times/day

at 30 min before meal;Sulfur acid capsules

0.6 g/time

1 time/day

at 30 min before breakfast. Besides the therapy of control group

patients in observation group were additionally treated with Jiawei Yigong powder

1 dose/day. The treatment course of both groups lasted for 4 weeks. Efforts were made to detect gastric emptying by B ultrasonic before and after treatment

record gastric half emptying time(T1/2 )

gastric emptying time(T)

score the symptom severity index (GCSI) of the stomach and mild paralysis

and test the levels of plasma motilin and gastrin before and after treatment. Result:Total effective rate in observation group was 91.8%

which was superior to 74.4% in control group (P<0.05). After treatment

gastric half emptying time and gastric emptying time in observation group were shorter than these in control group (P<0.05). Postprandial abdominal distension/early full

nausea and vomiting

abdominal distension score and gastroparesis total score in observation group were all lower than these data in control group (P<0.01). Levels of motilin and gastrin in observation group were lower than the standards in control group (P<0.01). Conclusion:Oral administration of Jiawei Yigong powder can reduce clinical symptoms of DGP patients

regulate gastrointestinal hormone

promote the gastric emptying

improve the clinical curative effect

and so is worth further studies.