Objective: To systematically evalate the safety and efficacy of intergrated traditional Chinese and western medicine in treating infantile rotavirus enteritis. Method: We searched The Cochrane Library

Embase

CNKI

Pubmed

CBM

VIP and Wanfang Data from database inception to June 27

2015.The Randomized Controlled Trials (RCTs) of intergrated traditional Chinese and western medicine in treating infantile rotavirus enteritis in any language were included

and recover into research references. Two researchers extracted data and assessed the literature quality separatedly

and made a Meta analysis using RevMan 5.3 software. Result: 28 RCTs involving 4 227 patients entered the inclusion criteria. The Meta analysis results showed that compared with western medicine

intergrated traditional Chinese and western medicine can significantly improve the clinical tatal effecctive rate[OR=5.10

95%CI(4.07

6.39)

P<0.000 01]

effectively shorten the defervescence time[MD=-0.30

95%CI(-0.46

-0.13)

P=0.000 4]

and shorten the time of diarrhoea[MD=-1.42

95%CI(-2.18

-0.66)

P=0.000 3]

increase the rate of turn rotavirus[OR=5.59

95%CI(3.55

8.78)

P<0.000 01]

the difference between two groups is statistically significant. ‘Funnel Plot’bias analysis results indicate that there may be a potential publication bias. Conclusion: The current results indicates that intergrated traditional Chinese and western medicine in treating infantile rotavirus enteritis can effectively improve the clinical effective rate

effectively shorten the defervescence time

and shorten the time of diarrhoea

increase the rate of turn rotavirus. However

the quality of methodology and report of small sample of RCTs are low

and the efficacy and safety of intergrated traditional Chinese and western medicine in treating infantile rotavirus enteritis still need more strict

large sample

randomized

double-blind trials to make the conclusion more reliable.