LIAN Bao-tao, XU Jing-li, GUO Zhen-lang, et al. Clinical Efficacy on Gegensu Injection Combined with Western Medicine for Curing Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(4): 189-194.
DOI:
LIAN Bao-tao, XU Jing-li, GUO Zhen-lang, et al. Clinical Efficacy on Gegensu Injection Combined with Western Medicine for Curing Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(4): 189-194. DOI: 10.13422/j.cnki.syfjx.2016040189.
Clinical Efficacy on Gegensu Injection Combined with Western Medicine for Curing Heart Failure
Objective: To systematically review the efficacy of Gegensu injection combined with western medicine for curing Heart failure. Method: Such databases as PubMed
CENTRAL
CNKI
VIP
EMbase
Wanfang and CBM were electronically searched to collect the randomized controlled trials. The document screening and quality evaluation were conducted to extractvalid data for a Meta-analysis. Result: Totally 16 RCTs involving 1 291 cases were included. The results of Meta-analysis showed that compared with the pure western medicine treatment
the combination of Gegensu injection and western medicine were superior in clinical comprehensive effect [OR=3.95
95%CI(2.84
5.49)]
left ventricular ejection fraction [MD=8.43
95%CI(3.41
13.45)]
stroke volume [MD=4.98
95%CI(3.20
6.75)]
cardiac output [MD=0.57
95%CI(0.19
0.94)]
cardiac index [MD=0.77
95%CI(0.33
1.20)] and reduction of heart rate [MD=9.71
95%CI(6.52
12.89)]
with significant statistical differences (P<0.05). Conclusion: Compared with the pure western medicine treatment
the combination of Gegensu injection and western medicine has a higher clinical efficacy in the treatment of heart failure.
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