Objective: To systematically review the clinical efficacy of Huangqin Tang in patients with ulcerative colitis (UC). Method: Databases such as PubMed

The Cochrane Library

Embase

Web of Knowledge

CBM

Wan fang Data

VIP and CNKI were searched for the randomized controlled trials about Huangqin Tang as the interventions for ulcerative colitis from database creation to January 24th

2015. Two reviewers independently screened literature

extracted data and evaluated methodological quality according to the inclusion and exclusion criteria. Then Meta-analysis was conducted using RevMan 5.2 software. Result: A total of 5 studies involving 309 patients were included. The results of Meta-analysis showed that

compared with sulfasalazine

Huangqin Tang can significantly improve the cure rate of ulcerative colitis[RR=1.54

95%CI(1.19

2.01)

P=0.001]

and significantly reduce the incidence of adverse reactions

but it can not increase the total effective rate of the treatment[RR=1.06

95%CI(0.97

1.17)

P=0.21]or reduce the clinical symptom scores of diarrhea

bloody purulent stool

tenesmus and stomachache. Conclusion: Huangqin Tang is batter than sulfasalazine in terms of curative rate and adverse reactions

but it still needs more studies for verification.