Cardiovascular disease is the first cause of death and disability among three major diseases

seriously impairing human health and life quality. Heart Qi deficiency syndrome is the most common traditional Chinese medicine syndrome of cardiovascular disease

so the study of animal models of heart Qi deficiency has important guiding effect and great application value for the prevention and treatment of cardiovascular disease.The experimental study is based on animal models

so the methods to establish animal models shall be in line with the actual development process of disease

and the evaluation indicators of animal models shall also correspond to the clinical indicators to the greatest extent. This article introduces the research status of the establishment and evaluation of animal models of heart Qi deficiency

proposes the problems existing in the establishment of heart Qi deficiency-animal models

and provides reference for the establishment and study of this animal model.