Improvement of Renal Function of Adenine-induced Kidney-yang Deficiency Rats Before and After Being Processed of Alpiniae Oxyphyllae Fructus in Suoquan Wan
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Improvement of Renal Function of Adenine-induced Kidney-yang Deficiency Rats Before and After Being Processed of Alpiniae Oxyphyllae Fructus in Suoquan Wan
Chinese Journal of Experimental Traditional Medical FormulaeVol. 22, Issue 5, Pages: 1-4(2016)
WU Shan-shan, GONG Xiao-meng, ZHANG Mei, et al. Improvement of Renal Function of Adenine-induced Kidney-yang Deficiency Rats Before and After Being Processed of Alpiniae Oxyphyllae Fructus in Suoquan Wan[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(5): 1-4.
DOI:
WU Shan-shan, GONG Xiao-meng, ZHANG Mei, et al. Improvement of Renal Function of Adenine-induced Kidney-yang Deficiency Rats Before and After Being Processed of Alpiniae Oxyphyllae Fructus in Suoquan Wan[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(5): 1-4. DOI: 10.13422/j.cnki.syfjx.2016050001.
Improvement of Renal Function of Adenine-induced Kidney-yang Deficiency Rats Before and After Being Processed of Alpiniae Oxyphyllae Fructus in Suoquan Wan
Objective: To discuss mechanism of stir fried with salt into the kidney-the kidney controlling water metabolism by analyzing effects of being processed of Alpiniae Oxyphyllae Fructus in Suoquan Wan on renal function of adenine-induced kidney-yang deficiency rats with much urine and expression of aquaporin-2(AQP-2). Method: Effects of being processed of Alpiniae Oxyphyllae Fructus in Suoquan Wan on urine volume
viscera indexes
creatinine (Cr)
urea nitrogen (BUN) and β2-microglobulin (β2-MG) in blood
AQP-2 mRNA and protein expression of adenine-induced kidney-yang deficiency rats were investigated. Result: Compared with the model group
each treatment group could reduce urine of rats
change of viscera indexes could be obviously inhibit
contents of Cr
BUN and β2-MG in blood significantly reduced
expression of AQP-2 mRNA and protein increased.After being processed with salt of Alpiniae Oxyphyllae Fructus in Suoquan Wan
effects strengthened obviously in comparison with the raw group. Conclusion: Alpiniae Oxyphyllae Fructus before and after being processed in Suoquan Wan have improving effects on renal function and protein expression of AQP-2 of adenine-induced kidney-yang deficiency rats
but effects strengthen obviously after salt processing.