PENG Jiu-man, CHAI Yao, PAN Min, et al. Transformation Relationship of Salvianolic Acids in Salviae Miltiorrhizae Radix et Rhizoma Under Heating,pH Conditions[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(5): 67-70.
DOI:
PENG Jiu-man, CHAI Yao, PAN Min, et al. Transformation Relationship of Salvianolic Acids in Salviae Miltiorrhizae Radix et Rhizoma Under Heating,pH Conditions[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(5): 67-70. DOI: 10.13422/j.cnki.syfjx.2016050067.
Transformation Relationship of Salvianolic Acids in Salviae Miltiorrhizae Radix et Rhizoma Under Heating,pH Conditions
Objective: To study the regularity of extraction time
pH of the phenolic acids in Salviae Miltiorrhizae Radix et Rhizoma. Method: Respectively investigates the Salviae Miltiorrhizae Radix et Rhizoma at different heating time
pH
and the reaction time of phenolic acids peak area change rule by High-performance liquid chromatography. Result: The content of salvianolic acid B was increasing and reached the maximum at 30 min
but it decreased from 1 to 6 h. Tanshinol
protocatechuic aldehyde
salvianolic acid A is the final product. Salvianolic acid A could be converted into Salvianolic acid C and iso-salvianolic acid C by alkaline hydolysis. Conclusion: Reveals transformation of phenolic acids under heating
pH conditions
providing theoretical support in future Chinese medicine production and clinical applications of Salviae Miltiorrhizae Radix et Rhizoma.
Simultaneous Content Determination of Salvianolic acid A, Salvianolic acid B, Tanshinol, Lithospermum Acid, Tanshinone Ⅱ in Crude Extract of Radix et Rhizoma by HPLC
Grade Evaluation of Salviae Miltiorrhizae Radix et Rhizoma Decoction Pieces Based on Relative Quality Constant
Quality Control of Salvianolic Acids Reference Extract
Effect of Effective Components of Salvia Miltiorrhiza on TGF-β1 Induced Interstitial Transformation of Pulmonary Epithelial Cells
Analysis of Extraction Technology for Preparations Containing Salviae Miltiorrhizae Radix Et Rhizoma in 2010 Edition of
Related Author
ZHANG Ying-feng
ZHU Li-xia
LIANG Dong-hui
Feng-yan NI
Hui-fang LYU
Xiao-he BI
Jia SHI
An-yi ZHAO
Related Institution
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
School of Pharmacy,Hebei University
Jiangxi University of Traditional Chinese Medicine