Objective: To systematically evaluate the clinical efficacy of Longdan Xiegan Tang (pill) for herpes zoster. Method: CNKI

VIP and Wanfang database were retrieved for the published literature on Longdan Xiegan Tang (pill) to treat herpes zoster with randomized or semi-randomized controlled trials to Mar of 2015.The studies which met the criteria were selected

and the quality evaluation and Meta statistical analysis were done using RevMan 5.3 software. Result: A total of 15 trials met the inclusion criteria

and Meta analysis showed that the relative risk (RR) and 95% confidence interval of total efficiency were 1.16 (1.12

1.21);MD values (95%CI) of blister stopping

incrustation

analgesia and heal time in the symptoms and signs were [-0.83 (-1.47

-0.18)

-0.47(-0.76

-0.18)

-0.62(-1.08

-0.16)

-1.25(-2.07

-0.44)]; OR (95%CI) of postherpetic neuralgia after treatment was [0.13(0.05

0.36)]. Conclusion: Compared with the western medicine

Longdan Xiegan Tang (pill) has high curing rate for herpes zoster

and has obvious advantages in improving the symptoms and signs and postherpetic neuralgia

but the low quality of included clinical research influences the reliability of the systematic review.