Objective: To discuss the efficacy of integrated Chinese and western medicine for vitality-deficiency and blood stasis type tubal pregnancy. Method: In this multicenter randomized controlled clinical study

a total of 300 patients of vitality-deficiency and blood stasis type tubal pregnancy were randomly divided into two groups:150 patients in the western medicine group were treated with mifepristone 150 mg po

once a day for 5 days. Based on the treatment of the western medicine group

150 patients in the integrated Chinese and western medicine group (integrated group) were also treated with ‘Modified Gongwaiyun No.1 Recipe’

and combined with Chinese patent drug for oral use

external use and intravenous drip. Effective rate of the both groups were detected. Time of serum Human chorionic gonadotropin-β(β-HCG) declining by more than 50% and 90%

time of the pelvic mass and pelvic effusion reducing by more than 50%

time of using medication and time of abdominal pain disappearing were calculated. Result: There were statistically significant differences in the total clinical effective rate between two groups (81.33% in integrated group VS 71.33% in western medicine group

P<0.05). Time of serum β-HCG declining by more than 50% and 90%

time of the pelvic mass and pelvic effusion reducing by more than 50%

and time of using medication in integrated group were shorter than those in western medicine group (P<0.05). Conclusion: Integrated Chinese and western medicine treatment was effective and reliable for tubal pregnancy (vitality-deficiency and blood stasis type)

and it can also shorten the treatment course of tubal pregnancy.