LI You-ran, GU Yun-fei, CHEN Yi-qi, et al. Meta-analysis of Chemotherapy Combined with Sijunzi Tang in Treatment of Patients with Colorectal Cancer[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(6): 204-209.
DOI:
LI You-ran, GU Yun-fei, CHEN Yi-qi, et al. Meta-analysis of Chemotherapy Combined with Sijunzi Tang in Treatment of Patients with Colorectal Cancer[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(6): 204-209. DOI: 10.13422/j.cnki.syfjx.2016060204.
Meta-analysis of Chemotherapy Combined with Sijunzi Tang in Treatment of Patients with Colorectal Cancer
Objective: To compare the chemotherapy combined with Sijunzi Tang and chemotherapy alone in clinical efficacy
quality of life
and side effects in treatment of colorectal cancer. Method: We searched for the literature of randomized controlled trials
published before October 2015 in both Chinese and English
comparing the chemotherapy combined with Sijunzi Tang and chemotherapy alone in clinical efficacy
quality of life
and side effects in treatment of colorectal cancer. Software Review Manager 5.3 was used to evaluate the quality of the included literature and conduct statistics work. Result: After strict screening
the 8 literature of randomized controlled trials were selected finally
involving 483 patients
the 245 cases with chemotherapy combined with Sijunzi Tang and 238 cases with chemotherapy alone. Results of Meta-analysis showed that there were statistically significant differences between two group in the quality of life and side effects (P<0.000 01). There was no significant difference in clinical efficacy (P=0.19). Conclusion: Sijunzi Tang can not only decrease the incidence of side effects of chemotherapy in patients with colorectal cancer
but also improve the quality of life for the patients.