CAO Lei, SHAN Li-fang, YANG Hong-mei, et al. Investigation of Extraction Process of Jinshui Ditan Oral Liquid[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(7): 31-34.
DOI:
CAO Lei, SHAN Li-fang, YANG Hong-mei, et al. Investigation of Extraction Process of Jinshui Ditan Oral Liquid[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(7): 31-34. DOI: 10.13422/j.cnki.syfjx.2016070031.
Investigation of Extraction Process of Jinshui Ditan Oral Liquid
Objective: To optimize extraction technology of Jinshui Ditan oral liquid. Method: Single factor tests were adopted to optimize extraction technology of aromatic water with extraction rate of volatile oil as index.With composite score of extracting amounts of hesperidin and icariin
yield of dry extract as index
orthogonal test was adopted to investigate effects of the amount of water
decocting time and times on extraction process.HPLC was employed to determine contents of hesperidin and icariin. Result: Aromatic water extraction process was distilled 4 hours with 10-fold water at a speed of 2 seconds per drop
then distilled 2 hours from aromatic water at the same speed
the final volume of distilled fragrance water was about 1.1 times weight of medicine.Water extraction technology was as follows:decocted thrice with 8-fold water
each time for 1.5 hour;extracting amounts of hesperidin and icariin were 27.77
15.30 mg · g-1
yield of dry extract was 40.13%. Conclusion: These optimized processes are stable and feasible
they can provide a reference for industrial production of Jinshui Ditan oral liquid.