Objective: To establish the HPLC fingerprints for Bawei Chenxiang pills

and provide scientific basis for further improving the quality standard. Method: Waters Xbridge Shield RP18 chromatographic column (4.6 mm×250 mm

5 μm) was used

with methanol-0.05% phosphoric acid solution as the mobile phase for gradient elution

at a flow-rate of 1.0 mL·min-1;the detection wavelength was set at 220 nm and column temperature was 25℃

with injection volume of 10 μL. Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine (2004A) was used to evaluate the HPLC fingerprints for 10 batches of Bawei Chenxiang pills. Result: Thirty-one common peaks were identified

and 4 common peaks were determined as gallic acid

costunolide

dehydrocostus lactone and dehydrodiisoeugenol. The similarity of 10 batches of Bawei Chenxiang pills was al ≥0.90. Conclusion: This method was proved simple

stable and reproducible

and can provide reliable basis for establishment of quality standards of Bawei Chenxiang pills.