Traditional Chinese Medicine Intervention Regulates Brain-gut Peptides of Irritable Bowel Syndrome

HUANG He-fei; CHEN Ying; ZHU Xiao-xin; CHEN Tao

doi:10.13422/j.cnki.syfjx.2016110208

您当前的位置：

首页 >

文章列表页 >

Traditional Chinese Medicine Intervention Regulates Brain-gut Peptides of Irritable Bowel Syndrome

更新时间：2024-01-04

- Traditional Chinese Medicine Intervention Regulates Brain-gut Peptides of Irritable Bowel Syndrome
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 22, Issue 11, Pages: 208-217(2016)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2016110208
  CLC： R285.5
- Published：2016
- 稿件说明：
移动端阅览
HUANG He-fei, CHEN Ying, ZHU Xiao-xin, et al. Traditional Chinese Medicine Intervention Regulates Brain-gut Peptides of Irritable Bowel Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(11): 208-217.
DOI：

HUANG He-fei, CHEN Ying, ZHU Xiao-xin, et al. Traditional Chinese Medicine Intervention Regulates Brain-gut Peptides of Irritable Bowel Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(11): 208-217. DOI： 10.13422/j.cnki.syfjx.2016110208.

摘要

肠易激综合征(irritable bowel syndrome

IBS)是一种常见的功能性肠道疾病

以腹痛或腹部不适伴排便习惯改变为主要临床表现

其发病原因迄今尚不完全清楚。具有激素和神经递质或调质双重作用的脑肠肽如促肾上腺皮质激素释放因子、P物质、胃动素、血管活性肠肽、降钙素基因相关肽、神经肽Y、生长抑素等

在IBS的发病机制中起重要作用。脑肠肽在体内的水平能够从一定程度上反映出IBS患者的疾病进程。中医药干预能够调节脑肠肽的异常变化

从而改善症状。本文以IBS患者和实验动物的脑肠肽变化及中医药干预带来的影响作一综述

以期为中医药防治IBS研究提供思路。

Abstract

Irritable bowel syndrome (IBS) is a common functional intestinal disease

with abdominal pain or discomfort associated with bowel habit change as the main clinical manifestation

and its etiology has not been fully clear yet. Brain-gut Peptides with dual functions of transmitters or modulators for hormones and nerves

such as corticotrophin releasing factor (CRF)

substance P (SP)

motilin (MTL)

vasoactive intestinal peptide (VIP)

calcitonin gene-related peptide (CGRP)

nerve peptide Y (NPY) and somatostatin(SS)

play an important role in the pathogenesis of IBS. In vivo brain-gut peptide levels in IBS patients can reflect their disease progression from a certain extent. Chinese medicine interventions can regulate the abnormal changes of brain-gut peptides

thereby improve the symptoms. This review was written based on the brain-gut peptide changes of IBS patients and experimental animals as well as the effects of traditional Chinese medicine interventions

to provide ideas for the research on traditional Chinese medicine prevention and treatment of IBS.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Prevention and Treatment of Colorectal Cancer Through Traditional Chinese Medicine Targeted Wnt Signaling Pathway： A Review

Regulation of Ferroptosis by Traditional Chinese Medicine for Colorectal Cancer Intervention： A Review

TCM Intervention in Prostate Cancer via Wnt/β-catenin Signaling Pathway： A Review

Traditional Chinese Medicine Intervention in Diabetic Nephropathy Based on PI3K/Akt Signaling Pathway： A Review

Intervention of Acute Lung Injury by Traditional Chinese Medicine via Regulating Oxidative Stress： A Review

Related Author

SHEN Jialin

ZHAO Xiaoying

XUE Chengcheng

LYU Yi

SHI Shang

MA Yuyuan

ZHOU Cheng

YANG Lin

Related Institution

Shaanxi University of Chinese Medicine

The Affiliated Hospital of Shaanxi University of Chinese Medicine

Changzhou Hospital of Traditional Chinese Medicine（TCM）

Xianyang Central Hospital

Shuguang Hospital Affiliated to Shanghai University of TCM

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰