Objective: To establish the method for quality control of Shujing Fangtong capsule. Method: TLC method was used to qualitatively identify Salvia Miltiorrhiza

Angelica Sinensis Radix

Olibanum and Myrrha in Shujing Fangtong capsule;the contents of paeoniflorin

naringin

neohesperidin and gsalvianolic acid B were simultaneously determined by HPLC

with acetonitrile-0.1% phosphoric acid solution as the mobile phase for gradient elution at a detection wavelength of 230 nm. Result: The TLC identification method was distinct and highly specific. Paeoniflorin

naringin

neohesperidin and gsalvianolic acid B showed good linear relationship in ranges of 25.30-506.00 mg·L-1 (r=1.000 0)

12.68-253.60 mg·L-1(r=0.999 9)

15.24-304.80 mg·L-1 (r=0.999 9) and 27.72-554.30 mg·L-1(r=0.999 9) respectively. The average recovery rate of samples was 100.69%(RSD 0.9%)

100.08%(RSD 1.6%)

100.85%(RSD 1.2%) and 100.85%(RSD 2.0%) respectively. Conclusion:This quality control method is simple

accurate and reproducible

which can be used to effectively control the quality of Shujing Fangtong capsule.