Efficacy of Glucosidorum Tripterygll Totorum Combined with Ambrette Capsules in Treatment of Diabetic Nephropathy and Its Effect on Inflammatory Factors
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Efficacy of Glucosidorum Tripterygll Totorum Combined with Ambrette Capsules in Treatment of Diabetic Nephropathy and Its Effect on Inflammatory Factors
Chinese Journal of Experimental Traditional Medical FormulaeVol. 22, Issue 12, Pages: 182-185(2016)
XU Xiao-jun, YE Shang-he, LU Xiao-wen. Efficacy of Glucosidorum Tripterygll Totorum Combined with Ambrette Capsules in Treatment of Diabetic Nephropathy and Its Effect on Inflammatory Factors[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(12): 182-185.
DOI:
XU Xiao-jun, YE Shang-he, LU Xiao-wen. Efficacy of Glucosidorum Tripterygll Totorum Combined with Ambrette Capsules in Treatment of Diabetic Nephropathy and Its Effect on Inflammatory Factors[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(12): 182-185. DOI: 10.13422/j.cnki.syfjx.2016120182.
Efficacy of Glucosidorum Tripterygll Totorum Combined with Ambrette Capsules in Treatment of Diabetic Nephropathy and Its Effect on Inflammatory Factors
Objective: To investigate the clinical efficacy of double dose glucosidorum tripterygll totorum combined with ambrette capsule in the treatment of diabetic nephropathy (DN) and observe its effect on the level of inflammatory factors. Method: The 126 patients with DN were divided into control group (with ambrette capsules alone) and observation group (double dose glucosidorum tripterygll totorum combined with ambrette capsules). 8 weeks were regarded as one course of treatment. Before and after the treatment
the inflammatory indexes in serum[interleukin (IL)-18
IL-6
hypersensitive C-reactive protein(Hs-CRP)]
liver and kidney function
24 h urinary protein. Result: The total effective rate in the observation group was significantly higher than that in the control group
with significant difference between two groups(P<0.05). After treatment
urinary protein was significantly decreased
renal function improved
plasma albumin increased
Hs-CRP
IL-18 and IL-6 significantly decreased in both groups (P<0.01). The observation group was significantly better than the control group in the comparison of above indexes (P<0.01). No liver function damage was seen. Conclusion: Double dose glucosidorum tripterygll totorum combined with ambrette capsules can reduce the inflammation indexes in serum
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