LI Lian-hua, CHEN Xin-chang, ZHANG Pei-qing. Professor ZHANG Pei-qing's Medication Regulatory for Membranous Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(12): 205-208.
DOI:
LI Lian-hua, CHEN Xin-chang, ZHANG Pei-qing. Professor ZHANG Pei-qing's Medication Regulatory for Membranous Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(12): 205-208. DOI: 10.13422/j.cnki.syfjx.2016120205.
Professor ZHANG Pei-qing's Medication Regulatory for Membranous Nephropathy
Objective: To analyze Professor ZHANG Pei-qing's medical experience for membranous nephropathy based on Traditional Chinese Medicine Inheritance Support System (V2.5). Method: ZHANG Pei-qing's prescriptions for membranous nephropathy patients were collected and logged into the Traditional Chinese Medicine Inheritance Support System(V2.5). Prescription frequency of drugs
combination of paired herbs and prescription characters were defined by using the software's integrated regularity analysis
improved mutual information
complex system entropy cluster
unsupervised hierarchical clustering and other data-mining methods and through Professor ZHANG Pei-qing's personal proofreading. Result: The 110 prescriptions were screened out and analyzed
involving 93 herbs. After determining the frequency of each herb and the association rules between all herbs
we got 16 core combinations and 8 new prescriptions
and these were confirmed as the core herbs for treating membranous nephropathy by Professor ZHANG Pei-qing. Conclusion: Professor ZHANG Pei-qing's prescriptions show outstanding characteristics in treating membranous nephropathy
with a high accuracy. The analytical results obtained by the Traditional Chinese Medicine Inheritance Support System were basically consistent with the professor's experience
indicating that the system can be used to analyze and summarize clinical experiences of famous veteran doctors of traditional Chinese medicine.