Objective: To observe the clinical effect of Ganhuangcao compound in the treatment of alcoholic fatty liver disease (AFLD). Method: The 90 patients with alcoholic fatty liver were randomly divided into treatment group and control group

with 45 cases in each group. Both of the two groups were injected with polyene phosphatidyl choline

and the treatment group was additionally given Ganhuangcao compound. The two groups were all treated for 4 weeks

and then their clinical efficacy

liver function

blood lipid

liver imaging changes and adverse drug reactions were observed. Result: The total effective rate was 80%in treatment group

and 60.22%in control group

indicating a statistically significant difference between the two groups (P < 0.05). And the treatment group was superior to the control group in clinical symptoms

liver function and blood lipid (P < 0.05)

with statistically significant differences in clinical symptoms

such as fatigue

jaundice

nacha

loose stools

liver function

such as alanine aminotransferase (ALT)

gamma-glutamyltranspeptidase (GGT)

γ-glutamine based transfer enzyme (γ-GT)

and blood lipids

such as low density lipoprotein cholesterol(LDL-C)

triglyceride (TG)(P < 0.05). Conclusion: Ganhuangcao compound is effective in treatment of alcoholic fatty liver

and worthy of clinical application.