Clinical Analysis of Manwei San in Treating Stomach Yin Deficiency Syndrome of Chronic Atrophic Gastritis

NING Yu-feng; YANG Cui lan; LI Fu shan

doi:10.13422/j.cnki.syfjx.2016130173

您当前的位置：

首页 >

文章列表页 >

Clinical Analysis of Manwei San in Treating Stomach Yin Deficiency Syndrome of Chronic Atrophic Gastritis

更新时间：2024-01-04

- Clinical Analysis of Manwei San in Treating Stomach Yin Deficiency Syndrome of Chronic Atrophic Gastritis
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 22, Issue 13, Pages: 173-176(2016)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2016130173
  CLC： R259
- Published：2016
- 稿件说明：
移动端阅览
NING Yu-feng, YANG Cui lan, LI Fu shan. Clinical Analysis of Manwei San in Treating Stomach Yin Deficiency Syndrome of Chronic Atrophic Gastritis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(13): 173-176.
DOI：

NING Yu-feng, YANG Cui lan, LI Fu shan. Clinical Analysis of Manwei San in Treating Stomach Yin Deficiency Syndrome of Chronic Atrophic Gastritis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(13): 173-176. DOI： 10.13422/j.cnki.syfjx.2016130173.

摘要

目的: 探讨慢萎散治疗慢性萎缩性胃炎(CAG)胃阴不足证的疗效以及对血清蛋白酶原Ⅰ(PGⅠ)和胃泌素(GS)水平的影响。方法: 选择符合条件的病例110例

按数字表法随机分为观察组和对照组各55例;对照组口服维酶素片0.2 g

4片/次

3次/d;观察组在对照组治疗的基础上给予慢萎散治疗;将慢萎散中药粉碎成细粉

每次9 g

温开水冲服

3次/d;所有患者均连续治疗3个月。比较两组治疗前后中医(TCM)症状积分、胃黏膜组织病理评分和治疗后临床疗效;检测两组患者血清PGⅠ和GS水平。结果: 观察组治疗后各中医症状评分均明显低于对照组(P < 0.01);观察组总有效率为90.74%

对照组为75.93%

观察组优于对照组(P < 0.05);观察组治疗后黏膜炎症、炎症活动度、腺体减少和肠上皮化生评分均明显低于对照组(P < 0.01);治疗后观察组PGⅠ和GS水平均明显高于对照组

比较差异均有统计学意义(P < 0.01)。结论: 慢萎散治疗慢性萎缩性胃炎胃阴不足证可明显改善患者临床症状、体征和胃黏膜组织病理评分

提高临床治疗效果

其作用可能与升高血清PGⅠ和GS水平相关。

Abstract

Objective: To investigate clinical efficacy of Manwei San in treating stomach Yin deficiency syndrome of chronic atrophic gastritis(CAG) and its influence on serum levels of Proteinase Ⅰ(PGⅠ) and gastrin(GS). Method: One hundred ten CAG cases were were randomly divided into observation group(55 cases) and control group (55 cases) referring to random number table.Cases in control group received Vitacoenzyme tablets 0.2 g (4 tablets/time

tid).Patients in observation group was treated with Manwei san

and Chinese herbal medicines were smashed and orally took with water(9 g/time

tid).Course of treatment was for 3 months for all cases.Scores of symptoms of traditional Chinese medicine(TCM) and pathology scores of gastric mucosa were compared between both groups pre-post treatment

and clinical efficacy was analysed after treatment.Serum levels of PGⅠand GS were detected in two groups before and after treatment. Result: Scores of TCM in observation group were obviously lower than those of control group(P < 0.01).The total efficacy of observation group was 90.74%

and control group was 75.93%with statistical difference between both groups (P < 0.05).After treatment

scores of inflammation of the mucosa

inflammation activity

reducing of gland

and intestinal metaplasia were remarkably lower than control group(P < 0.01).Compared to control group

serum levels of PGⅠand GS in observation group was obviously increased with statistical difference after treatment(P < 0.01). Conclusion: Manwei san could evidently improve clinical symptoms and signs

pathology scores of gastric mucosa

and clinical efficacy in treating stomach Yin deficiency syndrome of CAG

and its action may be related with elevating PGⅠand GS content in serum.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Senqi Xiaobi Granules on Serum Levels of GH, EGF and GAS in Rats with Chronic Atrophic Gastritis

Excavation of New Prescription for Chronic Atrophic Gastritis and Its Verification of Syndrome Type of Deficiency of Stomach Yin

Application of Ferroptosis Regulation in Chronic Atrophic Gastritis Based on Spleen Deficiency and Turbid Toxin

Effect of Coptisine on PI3K/Akt/mTOR Signaling Pathway in Chronic Atrophic Gastritis Rats

Current Status of Outcome Indicators in Randomized Controlled Trials of Traditional Chinese Medicine for Treating Chronic Atrophic Gastritis

Related Author

LI Jun-qing

LI Chun

LIU Xi

Wang Jing

SUN Jian-ning

SHAO Changming

WANG Hongyu

XIE Shanshan

Related Institution

Medical Department of Integrated Traditional Chinese and Western Medicine Hospital of Xinjiang Uygur Autonomous Region

College of Traditional Chinese Medicine， Xinjiang Medical University

Hebei University of Chinese Medicine

Hebei Hospital of Chinese Medicine

Hebei Key Laboratory of Turbidity Toxin Syndrome， Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research （Hebei）， Hebei Provincial Hospital of Traditional Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰