Methodological Quality Assessment in Systematic Review/Meta Analysis of Buyang Huanwu Tang in Treatment of Stroke

WENG Xiang-tao; HU Wei-xiong; ZHOU Qian-yi; ZHANG Shi-jing; LI Shao-shuo; CHEN Xin-lin

doi:10.13422/j.cnki.syfjx.2016140217

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Methodological Quality Assessment in Systematic Review/Meta Analysis of Buyang Huanwu Tang in Treatment of Stroke

更新时间：2024-01-04

- Methodological Quality Assessment in Systematic Review/Meta Analysis of Buyang Huanwu Tang in Treatment of Stroke
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 22, Issue 14, Pages: 217-221(2016)
- 作者机构：
- 作者简介：
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- DOI：10.13422/j.cnki.syfjx.2016140217
  CLC： R255.2
- Published：2016
- 稿件说明：
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WENG Xiang-tao, HU Wei-xiong, ZHOU Qian-yi, et al. Methodological Quality Assessment in Systematic Review/Meta Analysis of Buyang Huanwu Tang in Treatment of Stroke[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(14): 217-221.
DOI：

WENG Xiang-tao, HU Wei-xiong, ZHOU Qian-yi, et al. Methodological Quality Assessment in Systematic Review/Meta Analysis of Buyang Huanwu Tang in Treatment of Stroke[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(14): 217-221. DOI： 10.13422/j.cnki.syfjx.2016140217.

摘要

目的：评价补阳还五汤对比其他干预方法治疗中风的系统综述/Meta分析的方法学质量。方法：检索中国生物医学期刊网，维普，万方，中国知网，Cochrane图书馆数据库，纳入补阳还五汤对比其他干预方法治疗中风的系统综述/Meta分析的文献，检索时限截至2015年5月。采用Oxman-Guyatt Overview Assessment Questionnaire（OQAQ）量表对纳入文献进行评价。结果：共检索到92篇文献，最终纳入9篇文献，纳入的Meta分析主要存在以下问题：文献检索不全面、选择性偏倚控制不佳、原始文献方法学质量评价不标准、数据合并方法和前提准确性不高。原始文献实验设计存在以下缺陷：随机方法不明、没有开展分组隐蔽及盲法、没有报告意向性分析和不良反应事件、控制玷污或联合干扰描述不详细等。结论：近年来国内外补阳还五汤治疗中风的系统评价/Meta分析的文献逐渐增多，但能够达到高质量的系统评价/Meta分析较少，需进一步提高方法学水平和规范实验设计。

Abstract

Objective: To evaluate the methodological quality of the systematic review/Meta-Analysis (SR/MA) of Buyang Huanwu Tang in treatment of stroke by comparing with other interventions. Method: CMCC

Wanfang China National Knowledge Infrastructure

VIP and Cocranhe databases were searched to select the literature on systematic review/Meta-analysis (SR/MA) of Buyang Huanwu Tang and other interventions in treatment of stroke. The retrieval time limit was up to May 2015.Oxman-Guyatt Overview Assessment Questionnaire (OQAQ) Scale was used to evaluate the methodological and reporting quality of the eligible SR/MA. Result: A total of 92 SR/MA literature were obtained

and 9 of them were finally included. The included Meta analysis literature had the following shortcomings: no comprehensive literature search

high selection bias

poor methodological quality of the original articles

and poor accuracy of data consolidation method and premise. The experimental design of the original articles had the following shortcomings: unclear randomizatioon methods

no grouping concealment

no blinding

no reporting of intent-to-treat (ITT) analysis

uncertain co-intervention and contamination. Conclusion: The number of domestic and overseas literature on SR/MA of Buyang Huanwu Tang in treating stroke is gradually increasing in recent years

but few of them could reach high quality SR/MA

so it is necessary to improve the methodological quality and regulate the experimental design

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