Objective: This study was based on data of the transcriptome sequencing of Ganoderma

GLPRMT1

GLPRMT2 and GLPRMT3 were completed in detail by using bioinformatics method. Method: GLPRMT1

GLPRMT2 and GLPRMT3 were analyzed and predicted by the tools of bioinformatics in the following aspects:physical and chemical characteristics of amino acid sequences

function domain

hyophobicity or hydrophilicity

secondary structure and tertiary structure of protein

molecular phylogenetic evolution

and so on;expression levels of GLPRMT1

GLPRMT2 and GLPRMT3 were identified by FPKM from the transcriptome data. Result: Open reading frame finder indicated that GLPRMT1 and GLPRMT2 genes were full-length

while GLPRMT3 was partial;structural domain of GLPRMT1

GLPRMT2 and GLPRMT3 showed high homology with AdoMet-MTases domains;GLPRMT1

GLPRMT2 and GLPRMT3 had relative close relationship to PRMT3 family

PRMT1 family and PRMT5 family of fungus

respectively.From transcriptome data

transcripted level of GLPRMT2 was significantly higher than GLPRMT1 and GLPRMT3

and transcripted level of these three genes have increased significantly in growing periods of Ganoderma. Conclusion: These results provide basis for further understand the function of arginine methyltransferase and epigenetic regulation of Ganoderma.