GAO Yan-ping, WU Qiang, LIANG Jian, et al. Alkaloids from [J]. Chinese journal of experimental traditional medical formulae, 2016, 22(17): 67-70.
DOI:
GAO Yan-ping, WU Qiang, LIANG Jian, et al. Alkaloids from [J]. Chinese journal of experimental traditional medical formulae, 2016, 22(17): 67-70. DOI: 10.13422/j.cnki.syfjx.2016170067.
Objective: To study the chemical constituents of Tibet medicine Corydalis hendersonii. Method: The chemical constituents were isolated through combined techniques
silica gel
Sephadex LH-20
preparative TLC and semi-preparative HPLC
and their structures were determined on the basis of physicochemical properties
MS and NMR spectroscopic analysis and literature data. Result: Eleven alkaloids were isolated from the total alkaloids part of ethanol extract from C. hendersonii. Their structures were identified as 9-methyldecumbenine C(1)
protopine(2)
allocrytopine(3)
stylopine(4)
tetrahydroberberine(5)
tetrhydropalmatine(6)
tetrahydrocolumbamine(7)
ochotensimine(8)
fumariline(9)
dihydrosanguinarine(10)
and berberine(11). Conclusion: Compounds 3 and 5-11 were obtained from this species for the first time.
Characterization Four Kinds of Alkaloids in by HPLC-ESI-MS-MS
Advance on Chemical Constituents in
Alkaloids from
Nucleosides Chemical Constituents from
Chemical Constituents in Stem Barks of
Related Author
ZHANG Jia-yu
ZHANG Qian
ZHANG Fan
ZHANG Hong-xia
YIN Pei-hua
TU Peng-fei
ZHANG Chi
MA Yue
Related Institution
State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences, Peking University Health Science Center
Center of Scientific Experiment,Beijing University of Chinese Medicine
Key Laboratory for Standardization of Chinese Medicines,Ministry of Education, Shanghai Key Laboratory for Compound Chinese Medicines,Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine
Arura Tibetan Medicine Co.Ltd.
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences