Systematic Review of Umbilical Therapy of Traditional Chinese Medicine in Treating Ascites Due to Liver Cirrhosis

WU Zhu-lin; TAN Wan-jun; LIAN Bao-tao; PENG Li-sheng

doi:10.13422/j.cnki.syfjx.2016170177

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Systematic Review of Umbilical Therapy of Traditional Chinese Medicine in Treating Ascites Due to Liver Cirrhosis

更新时间：2024-01-04

- Systematic Review of Umbilical Therapy of Traditional Chinese Medicine in Treating Ascites Due to Liver Cirrhosis
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 22, Issue 17, Pages: 177-181(2016)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2016170177
  CLC： R575.2
- Published：2016
- 稿件说明：
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WU Zhu-lin, TAN Wan-jun, LIAN Bao-tao, et al. Systematic Review of Umbilical Therapy of Traditional Chinese Medicine in Treating Ascites Due to Liver Cirrhosis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(17): 177-181.
DOI：

WU Zhu-lin, TAN Wan-jun, LIAN Bao-tao, et al. Systematic Review of Umbilical Therapy of Traditional Chinese Medicine in Treating Ascites Due to Liver Cirrhosis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(17): 177-181. DOI： 10.13422/j.cnki.syfjx.2016170177.

摘要

目的：系统评价中药敷脐辅助西医常规治疗对肝硬化腹水的治疗效果及安全性。方法：计算机检索知网，万方，CBM，VIP，PubMed，Cochrane数据库和手工检索（时间从建库至2016年3月），筛选符合纳入标准的临床随机对照试验（RCT），依据改良后的Jadad量表行质量评价，提取数据并采用Review Manager 5.3进行Meta分析。结果：最终23篇文献符合纳入标准，纳入患者1 891例，Meta分析结果显示治疗组干预措施能提高临床疗效[OR=3.32，95% CI（2.58，4.27），P<0.00001]；改善中医证候评分[WMD=-1.85，95% CI（-2.49，1.20），P<0.00001]；减小患者腹围[WMD=-10.04，95% CI（-12.84，-7.25），P<0.00001]等。结论：中药敷脐辅助西医常规治疗对肝硬化腹水的效果优于单纯西医常规治疗，且安全性较好。

Abstract

Objective: To evaluate the therapeutic effect and safety of umbilical therapy of traditional Chinese medicine(TCM) combined with routine western therapy in treating ascites due to liver cirrhosis. Method: Databases

such as CNKI

Wanfang

CBM

VIP

PubMed

Cochrane Library

were searched (as at March 2016) to screen out relevant journals and the literature of randomized controlled trials(RCT). The quality of RCT was assessed by using Jadad scores

and Meta-analysis was performed with Review Manager 5.3 software. Result: Twenty-three articles were enrolled

involving 1891 patients. The results of Meta-analysis showed that intervention measures could improve the clinical effect[OR=3.32

95%CI (2.58

4.27)

P<0.00001]

increase TCM symptom complex score[WMD=-1.85

95%CI (-2.49

1.20)

P<0.00001]

reduce abdominal circumference[WMD=-10.04

95%CI (-12.84

-7.25)

P<0.00001]

et al. Conclusion: The combination of TCM and routine western therapy in treating ascites due to liver cirrhosis has a better efficacy and safe than the administration of routine western treatment along.

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