Comparison on Chemical Constituents and Pharmacological Effect of Gastrodiae Rhizoma Between Traditional Processing and Integration Processing

QIAN Yan; SHAN Ming-qiu; ZHANG Li

doi:10.13422/j.cnki.syfjx.2016180005

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Comparison on Chemical Constituents and Pharmacological Effect of Gastrodiae Rhizoma Between Traditional Processing and Integration Processing

更新时间：2024-01-04

- Comparison on Chemical Constituents and Pharmacological Effect of Gastrodiae Rhizoma Between Traditional Processing and Integration Processing
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 22, Issue 18, Pages: 5-8(2016)
- 作者机构：
- 作者简介：
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- DOI：10.13422/j.cnki.syfjx.2016180005
  CLC： R284;R285
- Published：2016
- 稿件说明：
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QIAN Yan, SHAN Ming-qiu, ZHANG Li. Comparison on Chemical Constituents and Pharmacological Effect of Gastrodiae Rhizoma Between Traditional Processing and Integration Processing[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(18): 5-8.
DOI：

QIAN Yan, SHAN Ming-qiu, ZHANG Li. Comparison on Chemical Constituents and Pharmacological Effect of Gastrodiae Rhizoma Between Traditional Processing and Integration Processing[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(18): 5-8. DOI： 10.13422/j.cnki.syfjx.2016180005.

摘要

目的：比较天麻一体化加工饮片与传统加工饮片在化学成分含量和药理效应方面的差异，阐述天麻饮片一体化加工工艺的合理性。方法：以天麻素和巴利森苷A，B，C，E的含量为指标，比较2种工艺所得产品化学成分含量的差异；以戊四氮致惊厥药理模型考察天麻2种工艺生产饮片的息风止痉药理作用。结果：天麻一体化加工饮片中天麻素和巴利森苷A，B，C，E质量分数分别为0.79%，2.04%，0.91%，0.23%，0.57%，传统加工饮片中则依次为0.39%，1.12%，0.64%，0.15%，0.54%。2种工艺所得饮片均具抗惊厥作用，但一体化加工饮片的抗惊厥作用强于传统分段加工工艺的饮片。结论：与传统分段加工工艺相比，一体化加工工艺降低了天麻的生产成本，提高了生产效率，且所得饮片有效成分含量较高、药理作用较好。

Abstract

Objective: To elucidate the rationality of integration processing technology based on comparison on chemical constituents and pharmacological effect of Gastrodiae Rhizoma between traditional processing and integration processing. Method: Taking contents of gastrodin and parishins as indexes

chemical constituents difference in Gastrodiae Rhizoma between traditional processing and integration processing was compared

effects of Gastrodiae Rhizoma on eclampsia model induced by pentylenetetrazole were observed to compare products with different processing technology. Result: Contents of gastrodin

parishin A

parishin B

parishin C and parishin E in products of integration processing were 0.79%

2.04%

0.91%

0.23%and 0.57%

they were 0.39%

1.12%

0.64%

0.15%and 0.54%in products of traditional processing.The anti-eclampsia effect of Gastrodiae Rhizoma produced with integrated processing technology was better than traditional processing technology. Conclusion: Compared with the traditional processing technology

the integrated processing technology is better in guaranteeing the quality of pieces

reducing the cost of production and increasing the production efficiency.

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Yan CHEN

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Related Institution

Provincial Key Laboratory of Pharmaceutics in Guizhou Province, State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for Development and Application of Ethnic Medicine and Traditional Chinese Medicine, Ministry of Education, School of Pharmaceutical Sciences, Guizhou Medical University

The Affiliated Hospital of Guizhou Medical University

Guangzhou University of Chinese Medicine

State Key Laboratory of Efficacy and Utilization of Medicinal Plants，Guizhou Medical University

Anhui Province Key Laboratory of Traditional Chinese Medicine，School of Pharmacy， Anhui University of Chinese Medicine

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