YE Tian-long, ZHOU Shi-gao, WEI Hua-feng. Professor XIA Xiang's Formula Rules for Treating Cardiovascular and Cerebrovascular Diseases with Qi-supplementing and Blood-activating Method[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(18): 169-175.
DOI:
YE Tian-long, ZHOU Shi-gao, WEI Hua-feng. Professor XIA Xiang's Formula Rules for Treating Cardiovascular and Cerebrovascular Diseases with Qi-supplementing and Blood-activating Method[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(18): 169-175. DOI: 10.13422/j.cnki.syfjx.2016180169.
Professor XIA Xiang's Formula Rules for Treating Cardiovascular and Cerebrovascular Diseases with Qi-supplementing and Blood-activating Method
Objective: To mine data and analyze the clinical cases of Professor XIA Xiang
in order to disclose his formula rules in treating cardiovascular and cerebrovascular diseases with Qi-supplementing and blood-activating method
and suggest methods and herbs for this disease. Method: The first-visit cardiovascular and cerebrovascular cases treated by Pro. XIA Xiang with Qi-supplementing and blood-activating method were collected
and the selected cases were entered in the Traditional Chinese Medicine Inheritance Support Platform (V2.5
TCMISS) to analyze the rules of Qi-supplementing and blood-activating method
herbs and symptoms through data mining. Then two disease entities with the largest number of cases were selected to further analyze the association rules of diseases
therapies and herbs. Result: Totally 89 formulas were collected
including 28 cases of headache and palpitation
17 cases of chest distress
15 cases of vertigo and 1 case of stroke. The common symptoms in order were fluster
chest distress
headache
dizzy
chest pain
insomnia
chill
fatigue
thirst
alliteration and tinnitus. They involved totally 220 types of herbs in 89 formulas
which were dominated by Qi-supplementing and blood-activating herbs
such as Astragali Radix
Salviae Miltiorrhizae Radix et Rhizoma
Puerariae Lobatae Radix
Codonopsis Radix and Chuanxiong Rhizoma. There were 8 and 15 common herbs treating headache and palpitation with the support score ≥18 and 15
involving 21 and 25 herbal pairs
there were 32 and 15 herbal combinations with the confidence score ≥95%
which produced 8 and 9 new formulas
respectively. Conclusion: TCMISS disclosed Pro. XIA Xiang's formulas rules for treating the cardiovascular and cerebrovascular diseases with the Qi-supplementing and blood-activating method
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