Objective: To observe the effects of Daozhi Paishi decoction on the urine metabolism in patients with Qi stagnation

blood stasis and damp-heat pouring down type kidney stone. Method: The 180 patients with kidney stone accompanied with abnormal urine metabolism were randomly divided into treatment group and control group. According to the different types of abnormal urine metabolism

all the patients received corresponding life guidance and prevention and treatment suggestions. In treatment group

patients also received Daozhi Paishi decoction

200 mL/time

bid

with 7 days as one treatment course

for a total of 4 courses. After that

the kidney stones were detected with B-ultrasound and X-ray

and the 24-hour urine biochemical detection was done with auto-biochemical analyzer. Result: After treatment

the number of cured cases and total effective rate in treatment group were higher than those in control group (P<0.05). The abnormal rate of urinemetabolism in both groups were was decreased after treatment (P<0.05). The rates of hypercalciuria

hyperoxaluria

high phosphorus urine and low urine output in treatment group were significantly lower than those in control group (P<0.05). The stone elimination rates in treatment group were higher than those in control group (P<0.05). The levels of 24 h urinary calcium

uric acid and oxalic acid in both groups were decreased after treatment (P<0.05)

while the levels of 24 h urinary magnesium and urine volume in both groups were increased after treatment (P<0.05). The level of 24 h urinary phosphorus in treatment group was decreased while the level of 24 h urinary citrate in treatment group was increased after treatment (P<0.05). The levels of 24 h urinary calcium

uric acid

oxalic acid

and urinary phosphorus in treatment group were lower than those in control group (P<0.05)

while the levels of 24 h urinary magnesium

citrate

and urine volume in treatment group were higher than those in control group (P<0.05). Conclusion: Daozhi Paishi decoction could accelerate the elimination of kidney stones and effectively intervene the urine metabolism of the kidney radiopaque calculus formers to prevent the development of the disease.